AI-guided trigger timing to optimize egg retrieval in IVF
An Artificial Intelligence Based Approach for Selecting the Optimal Day for Triggering.
This trial tests whether an AI program can guide monitoring and the ovulation trigger to produce similar or better IVF cycle results than decisions made by doctors.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 644 (estimated) |
| Ages | 18 Years to 42 Years |
| Sex | Female |
| Sponsor | Fundacion Dexeus Academic / other |
| Locations | 5 sites (Sabadell, Barcelona and 4 other locations) |
| Trial ID | NCT07515118 on ClinicalTrials.gov |
What this trial studies
In a randomized controlled design, participants undergoing controlled ovarian stimulation will be assigned to AI-guided monitoring and trigger timing using STIMAI® or to routine physician-led decision-making. The AI arm personalizes monitoring schedules and selects trigger and retrieval timing with the aim of maximizing oocyte yield while smoothing clinic workflow and reducing unscheduled procedures. Primary comparisons will include number of oocytes retrieved, fertilization-related outcomes, and clinical measures of cycle success, with safety and feasibility also recorded. All monitoring ultrasounds must be performed at one of the participating Dexeus Mujer centers in Catalonia.
Who should consider this trial
Good fit: People having controlled ovarian stimulation for IVF, oocyte donation, or elective fertility preservation who can attend all monitoring ultrasounds at the participating Dexeus centers are ideal candidates.
Not a fit: Patients requiring medically indicated fertility preservation or those unable to attend in-person monitoring visits are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, this approach could deliver equal or better IVF cycle outcomes while reducing clinic visits and weekend procedures for patients.
How similar studies have performed: Smaller studies and retrospective analyses have suggested AI can improve trigger timing and predict oocyte yield, but randomized evidence is still limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergoing COS for IVF with autologous oocytes, oocyte donation and elective fertility preservation with all monitoring USS (ultrasound scan) conducted at our centers. Exclusion Criteria: * Medically indicated fertility preservation * Inability to attend clinic visits for monitoring.
Where this trial is running
Sabadell, Barcelona and 4 other locations
- Dexeus Mujer Sabadell — Sabadell, Barcelona, Spain (Not_yet_recruiting)
- Dexeus Mujer Sant Cugat — Sant Cugat del Vallès, Barcelona, Spain (Not_yet_recruiting)
- Dexeus Mujer Reus — Reus, Tarragona, Spain (Not_yet_recruiting)
- Hospital Universitario Quiron Dexeus — Barcelona, Spain (Recruiting)
- Dexeus Mujer Tarragona — Tarragona, Spain (Not_yet_recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.