AI-guided trigger timing to optimize egg retrieval in IVF
Official title: An Artificial Intelligence Based Approach for Selecting the Optimal Day for Triggering.
Run by Fundacion Dexeus · NCT07515118 · Data updated 2026-11-12
This trial tests whether an AI program can guide monitoring and the ovulation trigger to produce similar or better IVF cycle results than decisions made by doctors.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 42 Years |
| Sex | Women only |
| Enrollment | 644 (estimated) |
| Sponsor | Fundacion Dexeus Academic / other |
| Locations | 5 sites (Sabadell, Barcelona and 4 other locations) |
| Status | Recruiting |
| Started | April 8, 2026 |
| Main results expected | April 2027 |
| Study ends | September 2027 |
| Registry record updated | April 22, 2026 |
| Trial ID | NCT07515118 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
People having controlled ovarian stimulation for IVF, oocyte donation, or elective fertility preservation who can attend all monitoring ultrasounds at the participating Dexeus centers are ideal candidates.
✕Probably not a fit
Patients requiring medically indicated fertility preservation or those unable to attend in-person monitoring visits are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In a randomized controlled design, participants undergoing controlled ovarian stimulation will be assigned to AI-guided monitoring and trigger timing using STIMAI® or to routine physician-led decision-making. The AI arm personalizes monitoring schedules and selects trigger and retrieval timing with the aim of maximizing oocyte yield while smoothing clinic workflow and reducing unscheduled procedures. Primary comparisons will include number of oocytes retrieved, fertilization-related outcomes, and clinical measures of cycle success, with safety and feasibility also recorded. All monitoring ultrasounds must be performed at one of the participating Dexeus Mujer centers in Catalonia.
Why it matters
Potential benefit: If successful, this approach could deliver equal or better IVF cycle outcomes while reducing clinic visits and weekend procedures for patients.
How similar studies have gone: Smaller studies and retrospective analyses have suggested AI can improve trigger timing and predict oocyte yield, but randomized evidence is still limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergoing COS for IVF with autologous oocytes, oocyte donation and elective fertility preservation with all monitoring USS (ultrasound scan) conducted at our centers. Exclusion Criteria: * Medically indicated fertility preservation * Inability to attend clinic visits for monitoring.
Where it's running
-
Hospital Universitario Quiron Dexeus
Barcelona, Spain Recruiting -
Dexeus Mujer Sabadell
Sabadell, Barcelona, Spain Not yet recruiting -
Dexeus Mujer Sant Cugat
Sant Cugat del Vallès, Barcelona, Spain Not yet recruiting -
Dexeus Mujer Reus
Reus, Tarragona, Spain Not yet recruiting -
Dexeus Mujer Tarragona
Tarragona, Spain Not yet recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.