Preventing Ovarian Hyperstimulation Syndrome in Women Undergoing IVF
Prophylaxis Against Ovarian Hyperstimulation Syndrome in PCOS Women
NA · Aljazeera Hospital · NCT06739759
This study is testing a new way to prevent ovarian hyperstimulation syndrome in women with polycystic ovary syndrome who are undergoing IVF by using different treatment methods.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 19 Years to 42 Years |
| Sex | Female |
| Sponsor | Aljazeera Hospital (other) |
| Locations | 2 sites (Giza and 1 other locations) |
| Trial ID | NCT06739759 on ClinicalTrials.gov |
What this trial studies
This study focuses on preventing ovarian hyperstimulation syndrome (OHSS), a serious complication that can arise during in vitro fertilization (IVF) procedures, particularly in women with polycystic ovary syndrome (PCOS). The approach involves using an antagonist protocol for IVF and a modified agonist protocol, supplemented with additional treatments such as hydroxychloroquine (HCQ). By closely monitoring and adjusting treatment protocols, the study aims to reduce the incidence and severity of OHSS in affected patients.
Who should consider this trial
Good fit: Ideal candidates for this study are women with polycystic ovary syndrome (PCOS) who are preparing for intracytoplasmic sperm injection (ICSI).
Not a fit: Patients who do not have polycystic ovary syndrome (PCOS) may not receive any benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce the risk of OHSS in women undergoing IVF, improving their overall treatment experience and outcomes.
How similar studies have performed: While there have been studies addressing OHSS, the specific combination of protocols and treatments in this study may offer a novel approach that has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women with PCOS coming for ICSI Exclusion Criteria: * Women who donnot have PCOS
Where this trial is running
Giza and 1 other locations
- Aljazeerah hospital — Giza, Egypt (RECRUITING)
- Algazeerah — Giza, Egypt (RECRUITING)
Study contacts
- Study coordinator: Mahmoud Alalfy, MD
- Email: mahmoudalalfy@ymail.com
- Phone: 01002611058
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Ovarian Hyper Stimulation Syndrome, OHSS, mild, Moderate, Severe