M-TAPA vs ESPB for lung function after gallbladder removal

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, controlled study compares two regional anesthesia techniques, M-TAPA and ESPB, in adults undergoing laparoscopic cholecystectomy. All participants receive standard general anesthesia and multimodal analgesia, with blocks performed before incision. The primary aim is to assess postoperative pulmonary function and analgesic use, with 60 patients randomized equally to each block. Blocks are ultrasound-guided and use identical local anesthetic dosing. Outcomes include respiratory function and pain control in the immediate postoperative period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18-70 years
* American Society of Anesthesiologists (ASA) physical status I-III
* Patients scheduled for elective laparoscopic cholecystectomy
* Patients who provide written informed consent
* Patients who are able to cooperate and perform pulmonary function tests (PFTs)

Exclusion Criteria:

* Coagulation disorders or anticoagulant therapy contraindicating regional anesthesia
* Infection at the planned block site
* Known allergy to local anesthetic agents
* Conversion to open surgery
* Hemodynamic instability
* Inability to cooperate with pulmonary function tests (PFTs)
* Pre-existing severe pulmonary disease (e.g., severe chronic obstructive pulmonary disease or restrictive lung disease)
* Chronic opioid use or opioid dependence
* Pregnancy or breastfeeding
* Active smokers
* Body mass index (BMI) \> 35 kg/m²

Where it's running

• Kayseri City Hospital
  Kayseri, Kocasinan, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Muhammed N Tekcan, Anesthesiology and Reanimation
• Email: mntekcan@gmail.com
• Phone: +905387931833

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.