Managing acute chest pain after combat-related thoracic injuries in Ukraine

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective multicenter trial compares two minimally invasive nerve-targeting procedures—cryoablation and radiofrequency ablation—in adults with acute thoracic combat injuries at tertiary centers in Vinnytsia, Rivne, and Lviv. Both procedures target intercostal nerves to provide localized analgesia and are performed under imaging and clinical monitoring to minimize risks. Key outcomes include pain scores (VNRS), opioid consumption, pulmonary function tests, functional recovery, quality of life, and procedure-related safety during the acute recovery period. Eligible participants are adults with moderate-to-severe chest pain (VNRS ≥4) who can provide informed consent and do not meet exclusion criteria such as severe coagulopathy or infection at the intervention site.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years
* Thoracic trauma from combat-related injuries
* VNRS ≥4 for acute thoracic pain
* Ability to provide informed consent

Exclusion Criteria:

* Severe coagulopathy
* Infection at intervention site
* Allergy to local anesthetics
* Inability to perform spirometry

Where it's running

• Communal enterprise "Yuri Semenyuk Rivne Regional Clinical Hospital" of Rivne Regional Council
  Rivne, Ukraine Recruiting

Study contacts

• Study coordinator: Maksym Barsa, MD, PhD
• Email: maxbars@email.ua
• Phone: +380952074098

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.