Breathing exercises to improve lung function in children with beta-thalassemia major

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Children with beta-thalassemia major who receive regular blood transfusions will perform a program of incentive spirometer exercises and guided breathing techniques (diaphragmatic, pursed-lip, and costal breathing). Pulmonary function tests and measures of functional capacity will be collected before and after the intervention, and oxygen saturation and heart rate will be monitored during and after transfusions. The protocol aims to detect changes in lung volumes, gas exchange, and exercise tolerance associated with the breathing program. Physiotherapists may use the findings to inform rehabilitation and daily-activity recommendations for this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Diagnosed as thalassemia \& subjected to blood transfusion
2. Their age range from 6 to 10 years old
3. Both sexes, male and female, will participate.
4. Subjects are able to follow simple verbal commands or instructions included in the procedures.

Exclusion Criteria:

1. Children with mental retardation or any other disability .
2. Children with visual or hearing defects.
3. Children with cardiovascular, chest pulmonary, and heart diseases.
4. Children with any postoperative cardiovascular, chest pulmonary, and heart conditions.

Where it's running

• Zagazig university hospitals.
  Zagazig, Egypt Recruiting

Study contacts

• Study coordinator: Rawan Muhammed Khairy, physical therapist
• Email: Roonyelsawy2@gmail.com
• Phone: 01125492020

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.