Looking at blood markers linked to bone, muscle, and energy metabolism

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective, single-center analysis of blood samples collected at IRCCS San Raffaele Hospital between January 1, 2006 and March 31, 2025. The work examines circulating bone formation markers (P1NP, osteocalcin, bone alkaline phosphatase) and resorption markers (CTx-I, NTx-I, DPD) alongside metabolic parameters and available clinical data. Statistical modeling will be used to explore interactions among bone, muscle, and energy metabolism, including possible links mediated by osteocalcin and adipokines. No interventions are performed because the project uses existing laboratory data and records.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 18 years.
* Blood sampling performed at the Laboratory Medicine Service of IRCCS San Raffaele Hospital, Milan, between January 1, 2006 and March 31, 2025.

Exclusion Criteria:

-Age \< 18 years

Where it's running

• IRCCS San Raffaele Hospital
  Milan, Italy, Italy Recruiting

Study contacts

• Study coordinator: Eleonora Sabetta, MD
• Email: sabetta.eleonora@hsr.it
• Phone: 0226435288

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.