Measuring energy needs during rehabilitation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will combine a doubly labeled water (DLW) database from healthy people with detailed, multimodal data collected from rehabilitation patients to build predictive models of energy requirements. Participants will undergo anthropometry, body composition, resting metabolic rate by indirect calorimetry, total energy expenditure by DLW and a metabolic chamber, activity monitoring, dietary intake and hunger ratings, sleep and cognitive testing, noninvasive brain monitoring, and gait analysis. Urine and other biological samples will be collected and DLW samples will be analyzed at a central laboratory, with machine learning used to develop injury-specific prediction algorithms. The goal is to characterize how energy metabolism changes across rehabilitation and to create tools to estimate individualized energy needs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male and female participants aged 20 to 70 years old;
* Rehabilitation patients with stroke or motor injuries;

Exclusion Criteria:

* Loss of autonomous mobility;
* Loss of consciousness;
* Individuals with metallic implants (e.g., pacemakers);
* Severe metabolic diseases (e.g., diabetes, other hereditary metabolic disorders);
* Patients with claustrophobia;
* Individuals with anorexia nervosa;
* Women in the preconception period, pregnancy, or lactation;
* Uremic patients;
* Inability to lie flat for one hour.

Where it's running

• Guangdong Jianxiang Hospital Group
  Foshan, Guangdong, China Recruiting

Study contacts

• Principal investigator: Xueying Zhang, PhD — Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
• Study coordinator: Xueying Zhang, Doctor
• Email: zhangxy@siat.ac.cn
• Phone: 86+18201296155

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.