Long-Term Recovery and Quality of Life after Sepsis in ICUs

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective multicentre observational cohort study in adults with sepsis admitted to ICUs. Data are collected at ICU admission, day 7, discharge, and at 28 days, 3 months, and 6 months after ICU admission to explore factors linked to long-term quality of life and other patient-centered outcomes. The study examines how patient characteristics, infection features, and centre practices relate to outcomes such as mortality, psychological and cognitive recovery, functional status, and return to work. Participating centers enroll consecutively with a target of 30 patients per center during a six-month period, up to a total of 600 participants. Geneva University Hospitals acts as the promoter, with international collaboration from several institutions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older
* Sepsis (community- or hospital-acquired) diagnosed on ICU admission, defined as either: (a) a diagnosis of sepsis made by the treating clinician at ICU admission AND fulfilment of Sepsis-3 criteria; or (b) a diagnosis of sepsis made by the treating clinician at ICU admission alone, where Sepsis-3 criteria are not routinely available according to local protocol

Exclusion Criteria:

* Refusal to participate, by the patient or the legal representative
* Inability to ensure follow-up (e.g. overseas residence, no fixed home address)
* Sepsis acquired in the ICU
* Patient admitted for palliative care

Where it's running

• Hopitaux Universitaires de Geneve (HUG)
  Geneva, Switzerland Recruiting

Study contacts

• Study coordinator: Hannah Wozniak, MD
• Email: hannah.wozniak@hug.ch
• Phone: +41 (7)95530291

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.