High-Intensity Peripheral Magnetic Stimulation for Traumatic Nerve Injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind, sham-controlled trial takes place at a single center and compares active high-intensity peripheral magnetic stimulation plus a standardized exercise program to sham stimulation plus the same exercise program in adults with unilateral traumatic peripheral nerve injury. Participants must have neuropathic pain, reduced muscle strength, and injury confirmation by EMG, with onset at least 3 months prior. The intervention consists of about 9 magnetic stimulation sessions over 3 weeks, delivered over the injured nerve, alongside daily personalized exercise therapy. Outcomes include pain, function, quality of life, and electrophysiological measures assessed at baseline, 4 weeks, and 8 weeks. Blinded assessors will evaluate outcomes to minimize bias.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 65 years
* Traumatic peripheral nerve injury
* Unilateral traumatic peripheral neuropathy confirmed by electromyography (EMG)
* Nerve injury occurring at least 3 months prior
* Douleur Neuropathique 4 (DN4) score ≥ 4
* Visual Analog Scale (VAS) score ≥ 4
* Manual Muscle Testing score \< 5
* No analgesic use, or stable analgesic therapy for the past month (no dose changes)

Exclusion Criteria:

* Active infection or malignancy
* Metal implant or shrapnel in the application area
* Electronic implants (e.g., cardiac pacemaker, spinal cord stimulator, deep brain stimulator)
* Central nervous system diseases
* Non-traumatic causes of neuropathy (e.g., radiculopathy, diabetic neuropathy, entrapment neuropathies, HIV-related neuropathy, trigeminal neuralgia)
* Complete nerve injury
* Injury involving three or more peripheral nerves or plexus injury
* History of peripheral nerve surgery or injection within the past 3 months
* Active psychiatric illness
* Coagulopathy

Where it's running

• Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
  Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Nurdan Korkmaz — Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
• Study coordinator: Hüseyin Anıl İnan, MD
• Email: dranilinan@gmail.com
• Phone: +905346159274

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.