Investigating the link between urinary tract infections and preeclampsia in pregnant women

Association of Urinary Tract Infection With Preeclampsia During Pregnancy

Observational Pakistan Air Force (PAF) Hospital Islamabad · NCT06962644

This study is trying to see if having a urinary tract infection during pregnancy is linked to developing preeclampsia in pregnant women.

Quick facts

Study typeObservational
Enrollment160 (estimated)
Ages18 Years to 35 Years
SexFemale
SponsorPakistan Air Force (PAF) Hospital Islamabad Academic / other
Locations1 site (Islamabad)
Trial IDNCT06962644 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the association between urinary tract infections (UTIs) and preeclampsia in pregnant women in Pakistan. It will enroll 160 participants, with half diagnosed with UTIs and the other half without, from the Obstetrics Department of PAF Hospital, Islamabad. The study will follow these patients until delivery to assess any potential correlations between the two conditions. The findings could provide insights into the impact of UTIs on pregnancy outcomes, particularly regarding preeclampsia.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant women aged 18 to 35 years, with a gestational age greater than 20 weeks, attending routine antenatal checkups.

Not a fit: Patients with chronic medical conditions such as diabetes, hypertension, or those who have undergone recent urological surgeries may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of the risks associated with UTIs during pregnancy and improve maternal and fetal health outcomes.

How similar studies have performed: While some studies have suggested a link between UTIs and preeclampsia, this specific investigation in Pakistan addresses a research gap and is considered novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients attending OPD for routine antenatal checkup
* Patients diagnosed with UTI as per operational definitions
* Gestational age greater than 20 weeks as per LMP
* Age between 18 to 35 years

Exclusion Criteria:

* History of medical conditions such as:
* Diabetes mellitus
* Chronic hypertension
* Chronic liver or kidney diseases
* Chronic pulmonary conditions
* History of urological surgical interventions in the past 3 months
* History of renal transplants
* Patients on immunosuppressive therapy
* History of comorbid conditions including:
* Diabetes mellitus
* Gestational diabetes mellitus
* Hypertension
* Chronic hepatic diseases
* Chronic liver diseases
* Chronic pulmonary diseases
* Ischemic heart diseases

Where this trial is running

Islamabad

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Urinary Tract InfectionPreeclampsiaPregnancyUrinary tract infectionTerm Birth
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.