Intra-Abdominal Pressure Changes During CRRT in Critically Ill Adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center prospective observational study of adults in the ICU receiving continuous renal replacement therapy. Intra-abdominal pressure will be measured via the bladder catheter at baseline and at 6, 12, 24, 48, and 72 hours after starting CRRT. The study will analyze how pressure changes relate to fluid balance, hemodynamics, vasopressor use, urine output, severity scores, duration of CRRT, and ICU/hospital stay, along with 30-day survival. No experimental treatment will be administered; the aim is to characterize temporal pressure trends and their associations with clinical variables.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Admission to the intensive care unit
* Receiving continuous renal replacement therapy (CRRT)
* Presence of an indwelling urinary (Foley) catheter for intra-abdominal pressure measurement

Exclusion Criteria:

* Pregnancy
* Open abdominal wound or open abdomen
* Neurogenic bladder
* History of bladder surgery
* Pelvic hematoma
* Pelvic fracture
* Presence of an intra-abdominal mass or other anatomical/technical condition that may compromise the reliability of intravesical pressure measurement

Where it's running

• SBÜ Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi
  Bursa, Bursa, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Cihan Sedat Aytünür, MD
• Email: dr.csa@msn.com
• Phone: +90 505 229 78 55

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.