Factors Influencing Outcomes in ECMO and Impella Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-center observational study follows adults treated with temporary mechanical circulatory support (ECMO or Impella) to see how metabolic status and thyroid hormone dynamics relate to 28-day and ICU mortality and other outcomes. Researchers collect medical history, nutritional status, functional capacity, and serial laboratory data including thyroid axis hormones, blood gases, and coagulation profiles. The aim is to identify independent predictors of mortality and characterize cardiac and non-cardiac complications and nutritional changes during critical illness. The study emphasizes non-cardiac factors such as endocrine dysfunction and nutritional status as potential drivers of outcomes in severe cardiogenic shock. Enrollment includes consecutive eligible patients with consent, making this a real-world cohort assessment in a high-volume center.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients (age ≥ 18 years)
* Treatment with ECMO and/or Impella support
* Informed consent provided by the patients next of kin/ legal representative

Exclusion Criteria:

* None

Where it's running

• Gottsegen Gyorgy National Cardiovascular Center
  Budapest, Hungary Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.