Improving sedation practices for critically ill patients on mechanical ventilation
Feasibility Study: Precision Sedation in Intensive Care Using Neurophysiologic and Respiratory Targets.
This study is testing a new way to manage sedation for critically ill patients on ventilators in the ICU to see if it makes them more comfortable and reduces risks from too much sedation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Oslo University Hospital Academic / other |
| Locations | 1 site (Oslo, Oslo) |
| Trial ID | NCT06991777 on ClinicalTrials.gov |
What this trial studies
This initiative aims to enhance sedation practices for patients in intensive care units (ICUs) who require mechanical ventilation. By utilizing neurophysiological and respiratory targets, the study seeks to optimize sedation levels, reducing the risks associated with oversedation and improving patient comfort. The approach involves a collaborative effort among healthcare providers at Oslo University Hospital to establish a more objective and effective sedation strategy. The goal is to minimize variability in sedation practices and improve overall patient outcomes in critical care settings.
Who should consider this trial
Good fit: Ideal candidates for this study are critically ill patients admitted to the ICU who are expected to require sedation for more than 24 hours.
Not a fit: Patients admitted for palliative care or those with restrictions on ventilator treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved patient comfort and reduced complications associated with prolonged mechanical ventilation.
How similar studies have performed: While there is ongoing research in sedation practices, this specific approach utilizing neurophysiological targets is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Admitted to ICU * Estimated need for sedation \> 24 hours Exclusion Criteria: * Patients admitted for palliative care * Patients admitted with restrictions in care (no ventilator treatment) * Contraindication for daily interruption of sedation
Where this trial is running
Oslo, Oslo
- Oslo University Hospital — Oslo, Oslo, Norway (Recruiting)
Study contacts
- Study coordinator: Theresa M Olasveengen, MD PhD
- Email: uxothe@ous-hf.no
- Phone: +4741419930
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.