Nutrition-based interventions to prevent cognitive decline
NUTRIMIND: Nutrition-based Interventions to Prevent Cognitive Decline
This study is testing if a 6-month nutrition program can help adults at higher risk for dementia keep their thinking skills sharp.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 55 Years to 85 Years |
| Sex | All |
| Sponsor | Instituto de Saude Publica da Universidade do Porto Academic / other |
| Locations | 2 sites (Porto, Portugal and 1 other locations) |
| Trial ID | NCT06853405 on ClinicalTrials.gov |
What this trial studies
This study evaluates the feasibility and effectiveness of a 6-month nutrition-based intervention aimed at preventing cognitive decline in adults at higher risk for dementia. Participants will be randomized into intervention and control groups, with the intervention group receiving nutrition education, cognitive training, and clinical consultations. The control group will receive a healthy recipes cookbook and an invitation to cooking workshops after data collection. Assessments will be conducted at baseline, after the intervention, and at a 6-month follow-up to measure various health and cognitive outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 55 to 85 years with a higher risk for dementia.
Not a fit: Patients with a diagnosis of dementia or major incapacity will not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce the risk of cognitive decline and improve the quality of life for older adults.
How similar studies have performed: Other studies have shown promising results with nutrition-based interventions for cognitive health, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged from 55 to 85 years old; * At least 4 years in the regular school system; * Higher individual risk for dementia defined as a score ≥6 points on the Cardiovascular Risk Factors, Aging and Dementia Dementia Risk Score (CAIDE). Exclusion Criteria: * Montreal Cognitive Assessment (MoCA) score lower than the validated cutoff points defined as 2 standard deviations below the normative reference value for the corresponding age and education in the Portuguese population; * Having a medical condition limiting the participation in the intervention (e.g., blindness, amputation…); * Lack of autonomy in daily activities; * Diagnosis of dementia or major incapacity.
Where this trial is running
Porto, Portugal and 1 other locations
- Instituto de Saúde Pública da Universidade do Porto — Porto, Portugal, Portugal (Recruiting)
- Faculty of Nutrition and Food Sciences, University of Porto — Porto, Portugal (Recruiting)
Study contacts
- Study coordinator: Daniela de Sousa, Master
- Email: daniela.sousa@ispup.up.pt
- Phone: +351222061820
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.