Improving CT diagnostics for stroke mimics
Official title: The Importance of Multimodal CT Examination in Stroke Mimics Diagnosis: a Prospective Observational Multicenter Study
Run by University Hospital Ostrava · NCT06045455 · Data updated 2026-11-12
This study is testing new CT imaging methods to see if they can better identify patients who are having stroke-like symptoms but don’t actually have a stroke, helping to avoid unnecessary treatments.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | University Hospital Ostrava Academic / other |
| Locations | 3 sites (Ostrava, Moravian-Silesian Region and 2 other locations) |
| Status | Recruiting |
| Started | October 1, 2023 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | January 16, 2024 |
| Trial ID | NCT06045455 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old presenting with acute focal neurological deficits within 24 hours of symptom onset.
✕Probably not a fit
Patients whose last period of normality is unknown or who have symptoms lasting more than 24 hours prior to examination may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational clinical research aims to enhance the accuracy of multimodal computer tomography (CT) diagnostics in identifying stroke mimics among patients with sudden neurological deficits. The study will involve patients over 18 years old who are suspected of having a stroke, utilizing advanced imaging techniques such as non-contrast CT, CT angiography, and CT perfusion. By comparing the effectiveness of these multimodal imaging methods against standard CT approaches, the study seeks to reduce inappropriate treatments and associated complications, while also analyzing the economic impact of improved diagnostics.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses of stroke mimics, reducing unnecessary treatments and improving patient outcomes.
How similar studies have gone: Other studies have shown promise in using advanced imaging techniques for stroke diagnosis, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- an acute focal neurological deficit (minimum 1 point on the National Institutes of Health Stroke Scale - NIHSS) within 24 hours from the onset of symptoms Exclusion Criteria: * the last period of normality is unknown prior to multimodal CT examination * the last period of normality is \>24 hours prior to multimodal CT examination * the diagnostic evaluation is incomplete * a final neurologic diagnosis cannot be determined
Where it's running
-
University of Ostrava
Ostrava, Moravian-Silesian Region, Czechia Recruiting -
University Hospital Ostrava
Ostrava, Moravian-Silesian Region, Czechia Recruiting -
Hospital České Budějovice
České Budějovice, South Bohemian Region, Czechia Recruiting
Study contacts
- Principal investigator: Michal Bar, prof.,MD,PhD — University Hospital Ostrava
- Study coordinator: Jiří Hynčica
- Email: jiri.hyncica@fno.cz
- Phone: 0042059737
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.