On-scene extracorporeal CPR (ECPR) in Ostrava
Official title: The Effectiveness of ECPR on the Scene and in Hospital for Out-of-hospital Cardi-ac Arrest (OHCA) in the Moravian-Silesian Region.
Run by University Hospital Ostrava · NCT07374289 · Data updated 2026-11-12
This tests doing ECMO (ECPR) at the scene for people ≤70 with witnessed out-of-hospital cardiac arrest who received bystander CPR to see if starting ECMO faster helps them survive with good brain function.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | University Hospital Ostrava Academic / other |
| Locations | 2 sites (Ostrava, Moravian-Silesian Region and 1 other locations) |
| Status | Recruiting |
| Started | January 30, 2026 |
| Main results expected | December 31, 2028 |
| Study ends | December 31, 2029 |
| Registry record updated | January 30, 2026 |
| Trial ID | NCT07374289 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people 70 years or younger with a presumed cardiac out-of-hospital arrest that was witnessed and who received immediate bystander CPR.
✕Probably not a fit
Patients with terminal malignant or chronic disease, unwitnessed arrests, no bystander CPR, likely non-cardiac causes, or older than 70 are unlikely to benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional program compares performing ECMO cannulation directly at the collapse scene by a mobile team versus transporting patients under mechanical chest compression for hospital cannulation. Eligible patients have a presumed cardiac cause, witnessed collapse, and bystander CPR, and teams aim to shorten the collapse-to-ECMO interval. The primary goal is to measure how much on-scene cannulation shortens the time from collapse to ECMO start; secondary outcomes compare survival and neurological status between the two approaches. The mobile ECPR effort is carried out by University Hospital Ostrava in collaboration with the regional emergency medical service.
Why it matters
Potential benefit: If successful, on-scene ECPR could substantially shorten time to ECMO and increase survival with good neurological outcomes in selected patients.
How similar studies have gone: Other ECPR programs have shown improved survival with good neurological outcomes in selected patients, but mobile on-scene ECPR is newer and less extensively studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Presumed cardiac aetiology of the cardiac arrest * Witnessed collapse * Bystander CPR * Estimated age ≤ 70 years * Body weight ≥15 Kg Exclusion Criteria: * Known terminal malignant disease * Known terminal chronic disease
Where it's running
-
Emergency Medical Services, Moravian-Silesian Region
Ostrava, Moravian-Silesian Region, Czechia Recruiting -
University Hospital Ostrava
Ostrava, Moravian-Silesian Region, Czechia Recruiting
Study contacts
- Principal investigator: Filip Burša, MD, PhD, EDEC — University Hospital Ostrava
- Study coordinator: Jiří Hynčica
- Email: jiri.hyncica@fno.cz
- Phone: +42059737
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.