Clinical trial Recruiting at 2 sites Interventional Ages 18 to 70

On-scene extracorporeal CPR (ECPR) in Ostrava

Official title: The Effectiveness of ECPR on the Scene and in Hospital for Out-of-hospital Cardi-ac Arrest (OHCA) in the Moravian-Silesian Region.

Run by University Hospital Ostrava · NCT07374289 · Data updated 2026-11-12

This tests doing ECMO (ECPR) at the scene for people ≤70 with witnessed out-of-hospital cardiac arrest who received bystander CPR to see if starting ECMO faster helps them survive with good brain function.

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment90 (estimated)
SponsorUniversity Hospital Ostrava
Academic / other
Locations2 sites (Ostrava, Moravian-Silesian Region and 1 other locations)
StatusRecruiting
StartedJanuary 30, 2026
Main results expectedDecember 31, 2028
Study endsDecember 31, 2029
Registry record updatedJanuary 30, 2026
Trial IDNCT07374289 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are people 70 years or younger with a presumed cardiac out-of-hospital arrest that was witnessed and who received immediate bystander CPR.

Probably not a fit

Patients with terminal malignant or chronic disease, unwitnessed arrests, no bystander CPR, likely non-cardiac causes, or older than 70 are unlikely to benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional program compares performing ECMO cannulation directly at the collapse scene by a mobile team versus transporting patients under mechanical chest compression for hospital cannulation. Eligible patients have a presumed cardiac cause, witnessed collapse, and bystander CPR, and teams aim to shorten the collapse-to-ECMO interval. The primary goal is to measure how much on-scene cannulation shortens the time from collapse to ECMO start; secondary outcomes compare survival and neurological status between the two approaches. The mobile ECPR effort is carried out by University Hospital Ostrava in collaboration with the regional emergency medical service.

Why it matters

Potential benefit: If successful, on-scene ECPR could substantially shorten time to ECMO and increase survival with good neurological outcomes in selected patients.

How similar studies have gone: Other ECPR programs have shown improved survival with good neurological outcomes in selected patients, but mobile on-scene ECPR is newer and less extensively studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Presumed cardiac aetiology of the cardiac arrest
* Witnessed collapse
* Bystander CPR
* Estimated age ≤ 70 years
* Body weight ≥15 Kg

Exclusion Criteria:

* Known terminal malignant disease
* Known terminal chronic disease

Where it's running

  • Emergency Medical Services, Moravian-Silesian Region
    Ostrava, Moravian-Silesian Region, Czechia
    Recruiting
  • University Hospital Ostrava
    Ostrava, Moravian-Silesian Region, Czechia
    Recruiting

Study contacts

  • Principal investigator: Filip Burša, MD, PhD, EDEC — University Hospital Ostrava
  • Study coordinator: Jiří Hynčica
  • Email: jiri.hyncica@fno.cz
  • Phone: +42059737

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.