Does fasting time affect post-induction low blood pressure after anesthesia?
Official title: Evaluation of the Relation Between Patient Fasting Time and the Occurrence of PIH (Post Induction Hypotension) - Prospective Trial
Run by University Hospital Ostrava · NCT07785635 · Data updated 2026-11-12
This observational study tests whether how long a patient fasts before anesthesia changes the chance of post-induction hypotension in adults undergoing planned procedures.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University Hospital Ostrava Academic / other |
| Locations | 1 site (Ostrava, Moravian-Silesian Region) |
| Status | Recruiting |
| Started | May 1, 2025 |
| Main results expected | September 2026 |
| Study ends | September 2026 |
| Registry record updated | August 25, 2026 |
| Trial ID | NCT07785635 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) scheduled for planned surgical or diagnostic procedures with general anesthesia and intubation.
✕Probably not a fit
Patients with factors unrelated to fasting time or with PIH due to other causes may not see a benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this single-center prospective study, researchers examine the relationship between preoperative fasting duration and the occurrence of post-induction hypotension after general anesthesia. The study considers multiple factors contributing to blood pressure drops, including anesthetic effects, ventilation, and relative fluid status due to fasting. Adults undergoing planned surgery or diagnostic procedures with intubation under general anesthesia are observed to assess associations between fasting length and PIH incidence and severity. No interventions are described beyond observation.
Why it matters
Potential benefit: If fasting duration is linked to PIH, clinicians may optimize preoperative fasting guidance to reduce hypotension risk.
How similar studies have gone: Prior knowledge supports that fluid status and vasoplegia contribute to PIH; this study explores a specific, modifiable factor (fasting time) and its impact.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Patients undergoing planned surgical or diagnostic procedure * Intubation under general anaesthesia Exclusion Criteria: * Pregnancy * Disagreement with participation in the study * Bowel preparation
Where it's running
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University Hospital Ostrava
Ostrava, Moravian-Silesian Region, Czechia Recruiting
Study contacts
- Principal investigator: Ondřej Jor, MD, PhD, MBA — University Hospital Ostrava
- Study coordinator: Jiří Hynčica
- Email: jiri.hyncica@fno.cz
- Phone: 0042059737
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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See if hypotension during anesthesia induction relates to tissue oxygen in open-heart surgery
This study tests whether post-induction hypotension in open-heart surgery patients can be predicted using arterial and tissue oxygenation measures.
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Wearable activity to see if daily movement predicts perioperative risk in older adults
This study tests whether preoperative activity measured by a wrist-worn accelerometer can help predict post-induction hypotension in adults aged 65 and older undergoing elective non-cardiac surgery.
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Predicting Post-Induction Hypotension in Elderly Patients Using Baroreflex Sensitivity and Machine Learning
Researchers are testing a machine learning approach that uses baroreflex sensitivity and other preoperative data to predict the risk of post-induction hypotension in people over 65 undergoing elective non-cardiac surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.