Mediterranean diet for managing weight and body composition after bilateral subthalamic nucleus deep brain stimulation in Parkinson's disease
Investigation of the Effect of the Mediterranean Diet on Nutritional Status in Parkinson's Patients Undergoing Bilateral Subthalamic Nucleus Deep Brain Stimulation
It will see if following a Mediterranean diet for three months after bilateral subthalamic nucleus deep brain stimulation helps adults with Parkinson's control weight and improve body composition.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 45 Years to 64 Years |
| Sex | All |
| Sponsor | Ankara University Academic / other |
| Locations | 1 site (Ankara, Ankara) |
| Trial ID | NCT07187739 on ClinicalTrials.gov |
What this trial studies
This randomized interventional trial will assign adults with Parkinson's disease undergoing bilateral subthalamic nucleus DBS to either Mediterranean diet guidance for three months or to continue their usual diet. Researchers will measure body weight, body composition, nutritional status, appetite, quality of life, and physical activity before and after the intervention. Eligible participants are 45–64 years old, have a Mini Mental State Examination score ≥24, and continue their antiparkinsonian medications. The trial is conducted at Ankara Etlik City Hospital and focuses on post-surgical dietary management to limit weight gain commonly seen after DBS.
Who should consider this trial
Good fit: Ideal candidates are adults aged 45–64 with Parkinson's disease scheduled for or having undergone bilateral STN DBS who have MMSE ≥24 and can follow dietary guidance while continuing antiparkinsonian therapy.
Not a fit: Patients with psychiatric illness, cognitive impairment (MMSE <24), or medical conditions requiring a special diet are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, the Mediterranean diet could reduce post-DBS weight gain and improve body composition, appetite, nutritional status, and overall quality of life.
How similar studies have performed: The Mediterranean diet has documented metabolic and general health benefits and has been associated with better outcomes in some Parkinson's cohorts, but using it specifically to prevent weight gain after STN DBS is relatively novel and not well established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being between 45-64 years of age * Signing informed consent * Undergoing STN DBS surgery * Continuing antiparkinsonian therapy * Those with a Mini Mental Test result of ≥24 points Exclusion Criteria: * Having any psychiatric illness * Those with a Mini Mental Test result of \<24 points * Those with a disease requiring a special diet other than Parkinson's Disease
Where this trial is running
Ankara, Ankara
- Ankara Etlik City Hospital — Ankara, Ankara, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Nursena ERSOY SÖKE, MsC
- Email: ersoynursena73@gmail.com
- Phone: (+90) 534 330 11 11
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.