Endoscopy versus esophagram to check the anastomosis after McKeown esophagectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective cohort from a single cancer center that reviewed patients who underwent McKeown esophagectomy and received either endoscopy or esophagram on postoperative day 7 to check the anastomosis. Decisions about starting oral intake were guided by the test findings, with patients showing poor healing on endoscopy monitored with weekly repeat endoscopy until healing was seen. Primary endpoints were diagnostic performance (sensitivity, specificity, PPV, NPV, and accuracy) for detecting anastomotic leak (AL) and the incidence of AL after oral intake. Secondary endpoints included time from surgery to AL diagnosis, time to AL healing, and safety outcomes with six months of follow-up.

Why it matters

Who can join: the full rules

Inclusion Criteria:

The inclusion criteria required patients to have routinely undergone either endoscopy or an esophagram for the postoperative evaluation of anastomosis.

Exclusion Criteria:

We excluded the patient with histologically confirmed benign tumors of the esophagus or esophagogastric junction and the patient who had incomplete data.

Where it's running

• Sun Yat-sen University Cancer Center
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Hong Yang, PhD.
• Email: yanghong@wy.sysucc.org.cn
• Phone: 13560405144

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.