Gamified visual training with occlusion for kids with anisometropic amblyopia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares a gamified visual training program combined with occlusion therapy to traditional occlusion therapy by itself in children with monocular anisometropic amblyopia. The approach uses two specially designed digital games, one serious touchscreen game and one augmented-reality game, to train visual function through parent–child interaction in home or other real-world settings. Outcomes will include changes in visual function, intrinsic motivation, and emotion regulation, assessed before and after the intervention. The goal is to develop a personalized, engaging home-based training product and service system that reduces medical anxiety and improves treatment adherence and overall clinical experience.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Clinically diagnosed with monocular anisometropic amblyopia.
2. Aged 4 to 7 years.
3. Able to cooperate with all examinations and comply with the amblyopia training regimen.
4. Provided signed informed consent.

Exclusion Criteria:

1. Severe developmental delay or cognitive impairment.
2. Serious systemic diseases.
3. Presence of organic ocular diseases (e.g., cataract, fundus diseases) or manifest strabismus.
4. Participation in any other eye-related interventional trial within the past 4 weeks.

Where it's running

• Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Jianing Ren
• Email: 981433535@qq.com
• Phone: +86 18800253186

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Augmented Reality Binocular Therapy for Adult Amblyopia

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• Gabor-based visual training for adults with amblyopia

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• Noninvasive brain stimulation plus augmented reality vision therapy for anisometropic amblyopia in adults

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• tDCS for paediatric amblyopia

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• Combined fluoxetine and patching to improve and maintain vision in amblyopia using OCTA and VEP

  This project will test whether adding fluoxetine to standard eye patching helps improve and maintain vision in people over 10 with amblyopia.

  Recruiting Minia University · Minya, Minya Governorate · NCT07417046

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.