Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Frailty, Nutrition, and Recovery in People Waiting for a Liver Transplant

Official title: Investigation of the Relationship Between Frailty, Sarcopenia, Malnutrition, and Psychosocial Parameters and Post-Transplant Outcomes in Liver Transplant Candidates

Run by Izmir Bakircay University · NCT07414095 · Data updated 2026-11-12

This project will test whether measures of frailty, muscle loss, nutrition, and psychological health can predict outcomes for adults (18–65) on the liver transplant waiting list in Turkey.

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Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment60 (estimated)
SponsorIzmir Bakircay University
Academic / other
Locations1 site (Izmir)
StatusRecruiting
StartedDecember 15, 2025
Main results expectedAugust 2026
Study endsAugust 2026
Registry record updatedFebruary 17, 2026
Trial IDNCT07414095 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18–65 who are listed for liver transplant at the participating center and can understand Turkish and complete simple physical tests.

Probably not a fit

Patients with severe orthopedic or neurological limitations, active serious extrahepatic malignancy, multiple organ transplants, or inability to follow verbal commands may not benefit from the assessments.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study enrolls adults listed for liver transplant and collects simple physical tests (strength, walking speed, daily activity), nutrition measures, and psychological screening before transplant. Researchers will link these multidimensional measures to clinical liver scores and track outcomes after transplant such as length of stay, complications, and survival. The design is longitudinal and descriptive, using routine clinical follow-up to relate pre-transplant status to post-transplant recovery. Findings aim to identify high-risk patients who might benefit from targeted pre- and post-transplant support.

Why it matters

Potential benefit: If successful, the findings could help clinicians identify patients at higher risk and tailor nutrition, physical therapy, and psychosocial support to improve recovery and survival.

How similar studies have gone: Previous observational studies have shown that frailty and sarcopenia predict worse outcomes after liver transplant, so this approach builds on existing evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being listed as a liver transplant candidate
* Age between 18 and 65 years
* Ability to understand the Turkish language

Exclusion Criteria:

* Presence of orthopedic and/or neurological problems severe enough to prevent completion of assessment tools
* Inability to understand verbal commands
* Being a recipient of multiple organ transplants
* Presence of serious active extrahepatic malignancy

Where it's running

  • Izmir University of Economics Medical Point Hospital
    Izmir, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.