Exploring the links between cancer, undernutrition, and sensory changes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the connections between newly diagnosed cancers of the oropharynx, oral cavity, colon, and liver, and the issues of undernutrition and sensory changes such as taste and smell. It aims to understand how these factors affect patients' dietary habits and overall quality of life. Participants will undergo various assessments, including tests, questionnaires, and biological sample evaluations, to gather comprehensive data on their nutritional status and sensory experiences. The study seeks to identify mechanisms and potential interventions to improve patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patient :

* With newly diagnosed cancer of the oropharynx, oral cavity, colon or liver (at any stage).
* For whom first-line treatment has been decided including radiotherapy, chemotherapy, immunotherapy and/or surgery.
* Able to follow all study procedures in accordance with the protocol.
* Have given their oral, free and informed consent to participate in the study.

Exclusion Criteria:

* Person not affiliated with national health insurance system
* Person subject to a legal protection measure (curatorship, guardianship)
* Pregnant women, women in labour or breastfeeding mothers
* Adults who is unable to give consent
* Minors
* Person unable to read, speak, write and understand French
* Patients with neuro-cognitive disorders (post-stroke, dyslexia, dyspraxia) or neuro-psychiatric disorders (dementia, autism) that make it impossible to assess taste sensoriality.
* Patients with olfactory or gustatory disorders documented prior to the disease
* Patient with another cancer currently being treated
* Patients with a systemic disease or physical trauma affecting taste perception
* Patients with kidney failure
* Patients with sinonasal polyposis
* Patients undergoing immunosuppressive treatment
* Patients with an estimated life expectancy of less than 3 months

Where it's running

• Chu Dijon Bourgogne
  Dijon, France Recruiting

Study contacts

• Study coordinator: Vanessa COTTET
• Email: Vanessa.cottet@u-bourgogne.fr
• Phone: 0380393487

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.