Exploring the link between jaw disorders and sleep issues

ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS

Observational IRCCS San Raffaele · NCT06975709

This study is trying to see if people with jaw problems also have sleep issues and how these two conditions might be connected.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorIRCCS San Raffaele Academic / other
Locations2 sites (Milan, Italy and 1 other locations)
Trial IDNCT06975709 on ClinicalTrials.gov

What this trial studies

This observational study investigates the prevalence of temporomandibular disorders (TMD) in patients suffering from various sleep disorders. Participants over the age of 18 will undergo a physical examination and complete questionnaires to assess their conditions. The study aims to clarify the relationship between TMD and sleep disorders, which has been poorly understood. By gathering data from affected individuals, the research seeks to provide insights into how these two health issues may be interconnected.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 years old who are experiencing specific sleep disorders such as insomnia or obstructive sleep apnea.

Not a fit: Patients with recent head or neck trauma, painful oral pathologies, or certain neurological and psychiatric conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnosis and treatment strategies for patients experiencing both TMD and sleep disorders.

How similar studies have performed: While the association between TMD and sleep disorders has been explored in some studies, this specific observational approach is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \>18 years
* Famale and Male
* Signature of the privacy information form
* Signature of the informed consent form of the protocol
* Subjects capable of understanding and wanting
* Subjects suffering from a sleep disorder (Insomnia,Hypersomnia,Restless legs syndrome,REM sleep behavior disorder,Narcolepsy,Obstructive sleep apnea syndrome (OSAS),Primary snoring, REM parasomnias,Nocturnal epilepsy)

Exclusion Criteria:

* Physical trauma to the head and neck area
* Painful oral pathologies (e.g. pulpitis, tooth fractures, tooth abscesses, tooth decay, canker sores and mucosal wounds)
* Recent dental treatments that may cause pain (e.g. tooth extraction, tooth root canal)
* Use of oral contraceptives
* Subjects not capable of understanding and wanting
* Patients suffering from neurological pathologies that may interfere with the completion of the questionnaires (ES dementia) or psychiatric pathologies or drug use as per DSM-5 criteria (including schizophrenia, bipolar, major depression, substance abuse, personality disorders).

Where this trial is running

Milan, Italy and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Temporomandibular DisordersSleep
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.