Virtual planning for total temporomandibular joint replacement

Three-dimensional Virtual Planning of Total Temporomandibular Joint Replacement Using Standardized Prosthesis.

Observational Lund University Hospital · NCT07373184

This project sees if virtual planning using standard (non‑custom) TMJ prostheses can plan jaw and implant positioning for patients who already had total TMJ replacement.

Quick facts

Study typeObservational
Enrollment30 (estimated)
SexAll
SponsorLund University Hospital Academic / other
Locations1 site (Lund)
Trial IDNCT07373184 on ClinicalTrials.gov

What this trial studies

This retrospective project uses imaging and surgical records from patients treated with total TMJ replacement at Lund University Hospital between 2010 and 2025. Investigators generate virtual models and run treatment simulations using standardized (off‑the‑shelf) TMJ prosthesis templates to plan jaw movements, prosthesis positioning, and fixation. Measured outcomes include maximal bone–prosthesis interface area, number of possible fixation screws, the ability to centre the mandibular component in the fossa, and the surgical movements required to correct severe malocclusion. The aim is to determine surgical feasibility of virtual planning with standardized prostheses and whether some benefits of custom implants can be delivered at lower cost.

Who should consider this trial

Good fit: Ideal candidates for inclusion are patients with severe TMJ pathology who previously underwent total TMJ replacement at the Department of Oral and Maxillofacial Surgery, Skåne University Hospital (Lund) between 2010 and 2025 and who have not had additional TMJ surgery afterwards.

Not a fit: Patients who had additional TMJ surgery after the replacement or whose anatomy requires bespoke, patient‑specific implants are unlikely to benefit from virtual planning using standardized prostheses.

Why it matters

Potential benefit: If successful, this approach could bring the advantages of virtual surgical planning to more patients at lower cost by enabling reliable planning with standardized TMJ prostheses.

How similar studies have performed: Patient‑specific TMJ prostheses and virtual surgical planning have seen clinical use and success, but applying the same virtual planning methods systematically to standardized off‑the‑shelf TMJ prostheses is less well tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with severe pathology in the temporomandibular joint.
* Previously treated with TMJ prosthesis at the department of Oral and Maxillofacial Surgery, Skåne University Hospital, Lund, Sweden.
* Treatments performed during year 2010 to 2025.

Exclusion Criteria:

\- Patients with additional surgical treatment of the TMJ after total TMJ replacement.

Where this trial is running

Lund

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Temporomandibular DisordersTemporomandibular Joint Ankylosistemporomandibular jointtemporomandibular disorderankylosisjoint prosthesistotal joint replacement
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.