Examining the link between sleep EEG and cognitive issues after surgery
Official title: Relationship Between Sleep EEG, Intraoperative EEG and Postoperative Cognitive Dysfunction
Run by Assistance Publique - Hôpitaux de Paris · NCT04481347 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is trying to see if monitoring brain activity during surgery can help understand why some patients have memory and thinking problems afterward.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris) |
| Trial ID | NCT04481347 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who are scheduled for surgery under general anesthesia.
✕Probably not a fit
Patients with severe pre-existing cognitive impairment or those undergoing emergency procedures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the relationship between sleep EEG patterns, intraoperative EEG readings, and the occurrence of postoperative cognitive dysfunction (POCD) in patients undergoing surgery. It aims to utilize quantitative EEG techniques to monitor brain activity during anesthesia, potentially allowing for better management of anesthetic dosages. By assessing preoperative cognitive status and EEG characteristics, the study seeks to identify factors that may contribute to cognitive decline following surgery, thereby improving patient outcomes.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring techniques that reduce the risk of cognitive dysfunction after surgery.
How similar studies have gone: Previous studies have shown promising results in using EEG monitoring to mitigate cognitive dysfunction, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Major patients (≥ 18 years ) * Eligible for an interventional radiology procedure or surgery under general anesthesia * Patients informed and having expressed their non-opposition to participation in this research Exclusion Criteria: * Patients under 18 years old * Severe pre-existing cognitive impairment (preoperative mini-mental state examination (MMSE) \< 24) * Patient opposed to protocol participation * Pregnant woman * Patient under judicial protection * Patient without affiliation to a social security scheme * Emergency procedure
Where it's running
-
AP-HP, Lariboisière Hospital, Department of Anesthesiology and Intensive Care
Paris, France Recruiting
Study contacts
- Principal investigator: Fabrice VALLEE, MD — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Joaquim MATEO, MD
- Email: joaquim.mateo@aphp.fr
- Phone: +33 (0)1 49 95 83 74
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.