Risk of delirium and cognitive problems after TUR-P in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study enrolling patients 65 years and older undergoing transurethral resection to identify perioperative factors linked to POCD and delirium. Researchers collect baseline data including MoCA scores, comorbidities, and frailty, then record anesthesia details and intraoperative events. Postoperative cognitive function and delirium are reassessed at defined time points using MoCA and CAM, and a multivariable model will be developed to predict risk. The goal is to create a clinically applicable risk score to guide perioperative care. The study uses a cohort design at Muğla Training and Research Hospital and aims to improve recognition and management of at-risk patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥65 years
* Scheduled for transurethral resection procedure
* ASA physical status I-III
* Able to provide informed consent
* Adequate cognitive function to complete preoperative assessment

Exclusion Criteria:

* Pre-existing diagnosis of dementia or severe cognitive impairment (MoCA \<18)
* Severe visual or hearing impairment preventing cognitive assessment
* History of psychiatric disease requiring antipsychotic or sedative medication
* Neurological disorders associated with increased delirium risk (e.g., Parkinson's disease, epilepsy)
* Inability to complete study assessments

Where it's running

• Muğla Training and Research Hospital
  Muğla, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Eylem Yasar, MD — Mugla Training and Research Hospital
• Study coordinator: Eylem Yasar, MD
• Email: eylemtarakci@gmail.com
• Phone: +905332392622

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.