Examining how muscle loss affects disease progression
Official title: Influence of Sarcopenia on the Course of the Diseases - Measured Using Ultrasound and Biochemical Markers
Run by Universitatsmedizin Mainz - 1. Medizinische Klinik · NCT06829290 · Data updated 2026-11-12
This study is trying to see how muscle loss affects the health and recovery of patients with liver cirrhosis, cancer, and those on breathing machines.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Universitatsmedizin Mainz - 1. Medizinische Klinik Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Mainz, Rhineland-Palatinate) |
| Status | Recruiting |
| Started | October 1, 2024 |
| Main results expected | October 1, 2026 |
| Study ends | October 1, 2028 |
| Registry record updated | February 17, 2025 |
| Trial ID | NCT06829290 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include oncology patients with gastrointestinal tumors, individuals with liver cirrhosis, and patients in intensive care units.
✕Probably not a fit
Patients who are incapable of consenting or have congenital muscle diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the impact of sarcopenia, a condition characterized by muscle loss, on the prognosis of patients with liver cirrhosis, cancer, and those requiring mechanical ventilation. The study will utilize ultrasound-based measurements and serological muscle markers to assess muscle quantity and quality, providing a simpler alternative to more complex diagnostic methods. By identifying the relationship between sarcopenia and disease outcomes, the research seeks to enhance early prognostic estimations for affected patients.
Why it matters
Potential benefit: If successful, this study could lead to improved prognostic assessments and tailored interventions for patients suffering from sarcopenia-related conditions.
How similar studies have gone: While the use of ultrasound for measuring sarcopenia is being explored, this approach is still in the validation phase and has not been widely tested in similar studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * oncological patient in the field of gastrointestinal tumors * patients with liver cirrhosis * patients attending the intensive care unit Exclusion Criteria: * patients incapable of consenting * patients with congenital muscle diseases
Where it's running
-
Universitatsmedizin Mainz
Mainz, Rhineland-Palatinate, Germany Recruiting
Study contacts
- Study coordinator: Wolfgang Maximilian Kremer Kremer, MD
- Email: maximilian.kremer@unimedizin-mainz.de
- Phone: 00496131175711
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.