Evaluating outcomes in critically ill patients after brain surgery

Comparison of the Predictive Value of APACHE II, SOFA, SAPS II, GCS and GCS-P Scores for In-hospital Mortality in Critically Ill Patients After Craniotomy

Observational Beijing Tiantan Hospital · NCT06762184

This study looks at adult patients who had brain surgery to see how well different scoring systems can predict their recovery and survival in the ICU.

Quick facts

Study typeObservational
Enrollment1600 (estimated)
Ages18 Years and up
SexAll
SponsorBeijing Tiantan Hospital Academic / other
Locations1 site (Beijing, Beijing)
Trial IDNCT06762184 on ClinicalTrials.gov

What this trial studies

This observational study reviews adult patients who underwent craniotomy and were admitted to the ICU at Beijing Tiantan Hospital from 2017 to 2020. It aims to collect and analyze patient data, including surgery details, complications, and outcomes, to assess the predictive accuracy of various severity scoring systems like APACHE II, SOFA, and SAPS II. Patients will be categorized based on survival outcomes, and the effectiveness of these scoring systems will be evaluated for different surgical indications. The study seeks to enhance understanding of post-craniotomy patient outcomes and the reliability of existing scoring methods.

Who should consider this trial

Good fit: Ideal candidates are adult patients who have undergone craniotomy and stayed in the ICU for more than 24 hours.

Not a fit: Patients who are pregnant, lactating, or enrolled in other clinical studies will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of outcome predictions for critically ill patients after craniotomy, leading to better patient management.

How similar studies have performed: Other studies have shown success in using severity scoring systems to predict outcomes in critically ill patients, making this approach well-supported.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients admitted to the ICU wards between 2017 and 2020
* Patients underwent craniotomy
* Patientshad an ICU stay of more than 24 hours

Exclusion Criteria:

* Pregnant or lactating women
* Patients enrolled in other clinical studies

Where this trial is running

Beijing, Beijing

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post-craniotomyCritical IllnessMortalitySeverity of Illness Scorescritical illpost-craniotomyAPACHE IISOFA
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.