Virtual Reality and Mental Practice to Improve Balance and Walking in Relapsing MS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Fifty-four adults with relapsing-remitting MS will be assigned to virtual reality training, mental practice, or a standard physical therapy program to compare effects on balance, risk of falling, and gait. The trial uses MRI-confirmed RRMS patients who can walk at least 10 meters and meet other safety criteria. Outcomes will include measures of balance, gait performance, and fall risk after the intervention. The study aims to determine which method, if either, provides greater benefits for mobility in RRMS.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with RRMS.
2. Patient's age will be range from 20 - 35 years..
3. Patients are able to walk 10 meter with or without assistance.
4. Patients with ≤ 6 according to an Expanded Disability Status Scale (EDSS).
5. Patients are cognitively able to follow instructions.
6. Patient's body mass index (BMI) will be ranged from 18.5 to 29.99 Kg/m2.

Exclusion Criteria:

1. Patients with MS relapse in the last 30 days.
2. Visual impairments interfering with VR.
3. Severe spasticity or orthopaedic deformity.
4. Recent musculoskeletal injury.
5. History of epilepsy or motion sickness with VR.

Where it's running

• Faculty of Physical Therapy, Cairo University
  Giza, Giza Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Ola Z Asal, BSc
• Email: ola25jan@gmail.com
• Phone: 00201023830508

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Treadmill-based virtual reality walking training for MS patients

  This study tests whether a treadmill with virtual reality and smart socks can help people with multiple sclerosis walk better and feel safer in daily life.

  Recruiting Shepherd Center, Atlanta GA · Atlanta, Georgia · NCT07927439

• REAL-MS: A Look at Autologous Stem Cell Transplant vs High-Efficacy MS Therapies in Real-World Care

  This study tests how AHSCT compares to high-efficacy MS medicines in adults treated in routine clinical care.

  Recruiting Imperial College London · London and 2 other locations · NCT07899502

• Tolebrutinib in real-world MS care for patients treated by clinicians

  This real-world study sees how tolebrutinib is used for multiple sclerosis patients and what outcomes look like in everyday practice.

  Recruiting Sanofi · Marina, Abu Dhabi Emirate · NCT07898371

• Pilates via live video vs. prerecorded videos for people with multiple sclerosis

  This study tests whether live, coach-led Pilates sessions through video calls are more beneficial than prerecorded Pilates videos for adults with MS.

  Recruiting Yuzuncu Yil University · Van · NCT07893925

• Cooling During Inpatient Rehab for People with MS

  This trial tests whether wearing a cooling vest during intensive training can reduce fatigue and improve walking, strength, balance, and cognition in people with multiple sclerosis during a 3-week inpatient rehab stay.

  Recruiting Klinik Valens · Valens, Canton of St. Gallen · NCT07852156

• Oral PRO-1562 in healthy adults and people with relapsing MS

  This study tests a once-monthly oral medicine called PRO-1562 to see if it is safe and helps remyelinate the brain in adults with relapsing multiple sclerosis and chronic vision problems.

  Recruiting Phase 1/2 Progentos Therapeutics · Adelaide, South Australia · NCT07826689

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.