Clinical trial Recruiting at 1 site Interventional Ages 17 to 100

Evaluating dental health after enamel reduction in orthodontic patients using clear aligners

Official title: Evaluation of Dental and Periodontal Health After Interproximal Enamel Reduction, in Patients in Orthodontic Treatment With Clear Aligners, and Comparison Between Laser Diode and Sodium Fluoride for the Treatment of Dentin Hypersensitivity

Run by University of Campania Luigi Vanvitelli · NCT06685016 · Data updated 2026-11-12

This study tests whether using a laser or fluoride can help reduce tooth sensitivity in orthodontic patients who are getting clear aligners and need some enamel removed.

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Quick facts

Study typeInterventional
Ages17 Years to 100 Years
SexAll
Enrollment30 (estimated)
SponsorUniversity of Campania Luigi Vanvitelli
Academic / other
Locations1 site (Naples)
StatusRecruiting
StartedJune 24, 2023
Main results expectedDecember 2024
Study endsDecember 2024
Registry record updatedNovember 14, 2024
Trial IDNCT06685016 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals in orthodontic treatment with clear aligners who require interproximal enamel reduction and have good oral and periodontal health.

Probably not a fit

Patients with enamel defects, cervical caries, periodontal disease, or a history of trauma or craniofacial anomalies may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the dental and periodontal health of patients undergoing orthodontic treatment with clear aligners who require interproximal enamel reduction (IPR). It compares the effects of using a laser diode versus sodium fluoride on dentin hypersensitivity during treatment. The study aims to determine if these interventions can reduce the incidence of dentin hypersensitivity compared to a control group. The methodology involves assessing dental health outcomes and sensitivity levels using a Visual Analog Scale (VAS).

Why it matters

Potential benefit: If successful, this study could lead to improved dental health outcomes and reduced sensitivity for patients undergoing orthodontic treatment with clear aligners.

How similar studies have gone: Other studies have shown promising results with similar approaches in managing dentin hypersensitivity during orthodontic treatments.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* to be in orthodontic treatment with clear aligners and this treatment requires interproximal enamel reduction;
* permanent dentition;
* good oral and periodontal health.

Exclusion Criteria:

* enamel defects;
* cervical caries;
* periodontal disease;
* history of trauma or craniofacial anomalies;
* pregnancy.

Where it's running

  • Multidisciplinary department of Medical-Surgical and Dental Specialties
    Naples, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.