Using resveratrol mouthwash to reduce bad breath in dental students
Official title: Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyromonas Gingivalis: A Randomized, Triple-blind Clinical Trial
Run by Al-Mustansiriyah University · NCT06882564 · Data updated 2026-11-12
This study is testing if a mouthwash with resveratrol can help dental students reduce bad breath caused by certain bacteria.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 20 Years to 24 Years |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | Al-Mustansiriyah University Academic / other |
| Locations | 1 site (Baghdad, Bab Al-Moadham) |
| Status | Recruiting |
| Started | January 5, 2025 |
| Main results expected | April 1, 2025 |
| Study ends | November 1, 2025 |
| Registry record updated | March 18, 2025 |
| Trial ID | NCT06882564 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are male and female undergraduate dental students aged 20 to 23 with halitosis due to gingivitis and no recent periodontal treatment.
✕Probably not a fit
Patients with systemic diseases, smokers, or those with periodontitis or other oral conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of a mouthwash containing resveratrol, an antioxidant, in reducing halitosis caused by Porphyromonas gingivalis among undergraduate dental students. A total of 54 participants will be divided into three groups: one receiving the resveratrol mouthwash, another receiving chlorhexidine as a positive control, and a third receiving a placebo. Over a week, participants will use the mouthwash twice daily, with compliance monitored through text reminders. Clinical assessments will be conducted to measure changes in gingival health and oral malodor before and after the intervention.
Why it matters
Potential benefit: If successful, this mouthwash could provide a novel and effective treatment option for managing halitosis and improving oral health.
How similar studies have gone: While the use of resveratrol in oral health is less common, similar studies using chlorhexidine have shown success in managing oral malodor, indicating potential for this novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Organoleptic tongue of scores \> 2 using (0-5scale) (Rosenberg and McCulloch, 1992) * Male and female undergraduate dental students without chemical plaque control measures for at least one weak * Male and female students with halitosis due to gingivitis * The age of students ranges from 20 to 23 years. * No periodontal treatment for at least one month * No systemic disease * No tobacco smoking * The patients must have at least 20 teeth Exclusion Criteria: * Smokers and alcoholics * Patient with periodontitis or pocket depth \> 6mm * Patient with orthodontics appliance * Open carious lesions, pericoronitis, dry socket, and fistula. * Patients with systemic disease and condition * taking medication in the last two weeks * Take garlic, onion, or licorice in the last 24 hours * using oral hygiene products in the last 24 hours * pregnant women * sinusitis, tonsilitis, and upper respiratory tract infection
Where it's running
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Mustansiriyah University
Baghdad, Bab Al-Moadham, Iraq Recruiting
Study contacts
- Principal investigator: Noor Aa Taher, B.d.s — Al-Mustansiriyah University
- Study coordinator: Noor Aa Taher, B.d.s
- Email: noor-aliabed@uomustansiriyah.edu.iq
- Phone: 07803432060 Ext. +964
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.