Evaluating blood platelets and biomarkers in healthy individuals
Official title: Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)
Run by The Cleveland Clinic · NCT05628974 · Data updated 2026-11-12
This study is testing how blood platelets work in healthy people to see if it can help us understand their role in blood vessel problems and find new treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | The Cleveland Clinic Academic / other |
| Locations | 1 site (Cleveland, Ohio) |
| Status | Recruiting |
| Started | May 1, 2020 |
| Main results expected | December 31, 2030 |
| Study ends | June 30, 2031 |
| Registry record updated | December 16, 2025 |
| Trial ID | NCT05628974 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy adults aged 18 to 65 years old.
✕Probably not a fit
Patients with hematopoietic diseases or those who have taken anticoagulant or antiplatelet medications in the past 10 days may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study at the Cleveland Clinic aims to investigate biomarkers in healthy individuals to uncover new mechanisms of platelet activation and their role in vascular inflammation and thrombosis. By comparing platelets from healthy participants to those from patients with vascular diseases, the study seeks to identify potential therapeutic targets. The research utilizes both in vivo animal models and human platelet samples to validate findings. The goal is to enhance understanding of platelet behavior in health and disease.
Why it matters
Potential benefit: If successful, this study could lead to new therapeutic strategies for preventing vascular diseases.
How similar studies have gone: Previous studies have shown success in identifying platelet activation pathways, suggesting that this approach may yield valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 to 65 years old * Healthy Male \& Female voluntary participants Exclusion Criteria: * Individuals who have taken anticoagulant or antiplatelet medications in past 10 days * Individuals with hematopoetic diseases
Where it's running
-
Cleveland Clinic
Cleveland, Ohio, United States Recruiting
Study contacts
- Principal investigator: Scott Cameron, MD, PhD — The Cleveland Clinic
- Study coordinator: Scott Cameron, MD, PhD
- Email: cameros3@ccf.org
- Phone: 216-444-1680
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.