Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Evaluating blood platelets and biomarkers in healthy individuals

Official title: Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)

Run by The Cleveland Clinic · NCT05628974 · Data updated 2026-11-12

This study is testing how blood platelets work in healthy people to see if it can help us understand their role in blood vessel problems and find new treatment options.

More Healthy Aging trials

Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment400 (estimated)
SponsorThe Cleveland Clinic
Academic / other
Locations1 site (Cleveland, Ohio)
StatusRecruiting
StartedMay 1, 2020
Main results expectedDecember 31, 2030
Study endsJune 30, 2031
Registry record updatedDecember 16, 2025
Trial IDNCT05628974 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy adults aged 18 to 65 years old.

Probably not a fit

Patients with hematopoietic diseases or those who have taken anticoagulant or antiplatelet medications in the past 10 days may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study at the Cleveland Clinic aims to investigate biomarkers in healthy individuals to uncover new mechanisms of platelet activation and their role in vascular inflammation and thrombosis. By comparing platelets from healthy participants to those from patients with vascular diseases, the study seeks to identify potential therapeutic targets. The research utilizes both in vivo animal models and human platelet samples to validate findings. The goal is to enhance understanding of platelet behavior in health and disease.

Why it matters

Potential benefit: If successful, this study could lead to new therapeutic strategies for preventing vascular diseases.

How similar studies have gone: Previous studies have shown success in identifying platelet activation pathways, suggesting that this approach may yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 to 65 years old
* Healthy Male \& Female voluntary participants

Exclusion Criteria:

* Individuals who have taken anticoagulant or antiplatelet medications in past 10 days
* Individuals with hematopoetic diseases

Where it's running

  • Cleveland Clinic
    Cleveland, Ohio, United States
    Recruiting

Study contacts

  • Principal investigator: Scott Cameron, MD, PhD — The Cleveland Clinic
  • Study coordinator: Scott Cameron, MD, PhD
  • Email: cameros3@ccf.org
  • Phone: 216-444-1680

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.