Evaluating blood platelets and biomarkers in healthy individuals
Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)
This study is testing how blood platelets work in healthy people to see if it can help us understand their role in blood vessel problems and find new treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | The Cleveland Clinic Academic / other |
| Locations | 1 site (Cleveland, Ohio) |
| Trial ID | NCT05628974 on ClinicalTrials.gov |
What this trial studies
This observational study at the Cleveland Clinic aims to investigate biomarkers in healthy individuals to uncover new mechanisms of platelet activation and their role in vascular inflammation and thrombosis. By comparing platelets from healthy participants to those from patients with vascular diseases, the study seeks to identify potential therapeutic targets. The research utilizes both in vivo animal models and human platelet samples to validate findings. The goal is to enhance understanding of platelet behavior in health and disease.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18 to 65 years old.
Not a fit: Patients with hematopoietic diseases or those who have taken anticoagulant or antiplatelet medications in the past 10 days may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to new therapeutic strategies for preventing vascular diseases.
How similar studies have performed: Previous studies have shown success in identifying platelet activation pathways, suggesting that this approach may yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 to 65 years old * Healthy Male \& Female voluntary participants Exclusion Criteria: * Individuals who have taken anticoagulant or antiplatelet medications in past 10 days * Individuals with hematopoetic diseases
Where this trial is running
Cleveland, Ohio
- Cleveland Clinic — Cleveland, Ohio, United States (Recruiting)
Study contacts
- Principal investigator: Scott Cameron, MD, PhD — The Cleveland Clinic
- Study coordinator: Scott Cameron, MD, PhD
- Email: cameros3@ccf.org
- Phone: 216-444-1680
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.