NVTIA Ergothioneine for Healthy Aging and Skin Health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind, placebo-controlled trial will compare daily NVTIA Ergothioneine to a matching placebo for 12 weeks in healthy adults aged 40 to 65. The study will measure biomarkers of oxidative stress and healthy aging, as well as skin elasticity, skin hydration, inflammatory markers, and safety. The goal is to determine if NVTIA Ergothioneine can support aging-related biomarker profiles and skin health in a generally healthy population. Participants will be assessed through lab tests and skin measurements, with safety monitoring throughout the trial. The trial aims to provide clinical evidence for the potential benefits of a branded ergothioneine ingredient as a dietary supplement for aging and skin health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants must meet all of the following criteria:

  * Male or female adults aged 35 to 55 years.
  * Generally healthy as determined by medical history, physical examination, and screening assessments.
  * Body Mass Index (BMI) between 18.5 and 29.9 kg/m².
  * Willing and able to provide written informed consent.
  * Willing to maintain their usual diet, physical activity, and lifestyle throughout the study period.
  * Willing to avoid the use of other antioxidant, anti-aging, or nutritional supplements during the study period unless approved by the investigator.
  * Able and willing to comply with all study procedures and scheduled visits.

Exclusion Criteria:

* Participants meeting any of the following criteria will be excluded:

  * History of clinically significant cardiovascular, hepatic, renal, gastrointestinal, endocrine, neurological, or psychiatric disease.
  * Current diagnosis of diabetes mellitus requiring medication.
  * Active inflammatory or autoimmune disease.
  * History of malignant disease within the previous five years.
  * Pregnancy, breastfeeding, or planning pregnancy during the study period.
  * Known allergy or hypersensitivity to ergothioneine or any ingredient of the study product.
  * Use of antioxidant supplements, anti-aging supplements, or investigational products within 30 days before enrollment.
  * Current smoker or history of heavy alcohol consumption.
  * Participation in another clinical trial within the previous 30 days.
  * Any medical condition or laboratory abnormality that, in the opinion of the investigator, may interfere with study participation or interpretation of study results.

Where it's running

• Dhaka Central International Medical College & Hospital
  Dhaka, Bangladesh Recruiting

Study contacts

• Study coordinator: Daniel Harris
• Email: work.director@dcimch.com
• Phone: +880 1712 345678

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.