Impact of muscle degeneration on chronic low back pain after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between muscle atrophy and chronic low back pain in patients undergoing lumbar decompression surgery for conditions like lumbar spinal stenosis and disc herniation. It follows a cohort of patients preoperatively and at multiple postoperative intervals to assess outcomes and the role of muscle degeneration in pain persistence. The study aims to improve rehabilitation strategies and predict surgical outcomes based on muscle condition. Imaging tests will be conducted to evaluate muscle status before and after surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. adults 18 years of age and older;
2. with symptoms of lumbosacral neural compression (radiculopathy or neurogenic lameness);
3. failed conservative treatment for at least 6 weeks;
4. undergoing surgery for neural decompression (discectomy and / or foraminotomy and / or hemilaminectomy);
5. with complete pre and postoperative medical records in all evaluations.

Exclusion Criteria:

1. need for lumbar arthrodesis;
2. deep infection requiring surgical cleaning;
3. patients submitted to joint facet rhizotomy;
4. active rheumatologic disease, including seronegative arthropathies.

Where it's running

• Hospital Israelita Albert Einstein
  São Paulo, São Paulo, Brazil Recruiting

Study contacts

• Principal investigator: Alberto Gotfryd, PhD — Phisician
• Study coordinator: Alberto Gotfryd, PhD
• Email: albertocoluna@yahoo.com.br
• Phone: 5511995925225

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.