Clinical trial Recruiting at 1 site Interventional Ages 18 to 30

Acute Effects of Neurodynamics on Hamstrings in Athletes

Official title: Acute Effects of Neurodynamics on Strength and Endurance in Athletes: A Randomized Control Trial

Run by High Point University · NCT07721220 · Data updated 2026-11-12

This study tests whether neurodynamic techniques can help athletes keep or improve hamstring strength and endurance.

Quick facts

Study typeInterventional
Ages18 Years to 30 Years
SexAll
Enrollment45 (estimated)
SponsorHigh Point University
Academic / other
Locations1 site (High Point, North Carolina)
StatusRecruiting
StartedJune 15, 2026
Main results expectedJuly 2026
Study endsJuly 2026
Registry record updatedJuly 22, 2026
Trial IDNCT07721220 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Athletes or individuals aged 18–30 who are actively engaged in organized sport or structured athletic conditioning and can safely participate in strength and maximal-effort testing.

Probably not a fit

Individuals outside the age range, with recent lower-extremity surgery, or with conditions markedly altering neuromuscular performance may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines the immediate impact of neurodynamic techniques on hamstring strength and muscular endurance in athletes. Participants will undergo interventions such as sciatic slider, sciatic tensioner, mechanically loaded sciatic neurodynamic floss, and elastic resistance bands. The goal is to see if these techniques can maintain or enhance hamstring performance and nerve mobility during athletic activity. Results may help physical therapists tailor exercise and hands-on treatments for hamstring and sciatic nerve–related conditions. The study is conducted at High Point University with eligible athletes or structured resistance-trained individuals.

Why it matters

Potential benefit: If successful, participants may experience better hamstring function and reduced risk of future injuries through improved nerve mobility and strength preservation.

How similar studies have gone: Prior work in neurodynamics shows promise for improving nerve mobility and function, but this exact acute intervention in athletes is comparatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants must be between 18 and 30 years of age.
* Must be able to read, understand, and provide informed consent, in English.
* Must be currently participating in an organized sport (e.g. collegiate, club, or competitive recreational level) or engaging in structured resistance training and athletic conditioning for recreational sports events (e.g 5k, marathon, Crossfit, Hyrox, etc).
* Medically stable with no known contraindications to physical exertion.
* Cleared for participation in strength or maximal-effort isometric testing.
* Be able to perform lower extremity isometric testing without pain that limits maximal effort.
* Must have 2 lower extremities capable to producing full range knee flexion and extension range of motion.
* No medical condition that significantly alters lower extremity neuromuscular performance.
* No history of lower extremity surgery in the past 12 months.

Exclusion Criteria:

* Individuals younger than 18 or older than 30.
* Acute lower extremity injury in the last 12 weeks.
* Lower extremity surgery within the last 12 months.
* Pain in either lower extremity that would limit maximal physical exertion.
* History of neurological disorders, including but not limited to: Neuropathy, Stoke, MS, Parkinson's Disease, etc.
* Use of medications that significantly impact neuromuscular performance, strength or fatigue.
* No supplementation that affects neuromuscular performance, strength, or fatigue.
* Unable to read and understand English.
* Not in a vulnerable population: Pregnant, mentally or physically challenged, cognitively impaired.

Where it's running

  • High Point University
    High Point, North Carolina, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.