Database for Parkinson's Disease and Related Disorders
Parkinson's Disease and Movement Disorders Clinical Database
University of Pennsylvania · NCT04997642
This study is creating a detailed database of information from people with Parkinson's disease to help researchers understand how the disease progresses and how different treatments work over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Pennsylvania (other) |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Trial ID | NCT04997642 on ClinicalTrials.gov |
What this trial studies
This observational study creates a comprehensive research database that includes demographic and family history information, clinical symptoms, neuropsychological profiles, treatments, biological samples, and brain images of patients with Parkinson's disease and related disorders. Participants are seen annually for the first four years and biennially thereafter, allowing for longitudinal analysis of the disease's progression and treatment effects. The database aims to facilitate research on the long-term effects of Parkinson's disease, identify genetic factors, and improve patient management strategies.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with Parkinson's disease who may also have mild cognitive impairment or dementia.
Not a fit: Patients without a diagnosis of Parkinson's disease will not benefit from this study.
Why it matters
Potential benefit: If successful, this database could enhance understanding of Parkinson's disease and lead to improved treatment and management strategies for patients.
How similar studies have performed: Other studies utilizing similar observational databases have shown success in advancing understanding and treatment of neurodegenerative diseases.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Any person who receives medical care for the diagnosis of Parkinson's disease with mild cognitive impairment (MCI) or dementia may be eligible to participate in the research database. There are no limitations for database participation based on age, disease severity or presence of cognitive impairments, as long as the person is able to complete the research assessments. Exclusion Criteria: Absence of Parkinson's disease diagnosis. There are no limitations for database participation based on age, disease severity or presence of cognitive impairments, as long as the person is able to complete the research assessments.
Where this trial is running
Philadelphia, Pennsylvania
- University of Pennsylvania — Philadelphia, Pennsylvania, United States (RECRUITING)
Study contacts
- Study coordinator: Eugenia Mamikonyan
- Email: eugenia.mamikonyan@pennmedicine.upenn.edu
- Phone: 215-615-3085
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Parkinson Disease, Parkinson Disease Dementia, Lewy Body Parkinson Disease, Lewy Body Dementia With Behavioral Disturbance