Examining the effects of combined therapy for schizophrenia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the effectiveness of combining Cognitive Behavioural Therapy for Psychosis (CBTp) and Cognitive Remediation Therapy (CR) for individuals with schizophrenia-spectrum disorders. It aims to identify predictors of treatment response to determine whether patients benefit more from the combined intervention or from either therapy alone. The study will be one of the largest of its kind, focusing on improving functional recovery and community functioning, which are often inadequately addressed by current treatments. By evaluating both the combined intervention and individual responses, the trial seeks to provide insights into optimizing treatment strategies for this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18-65 years
* Diagnosed with schizophrenia-spectrum disorders
* Can read, write, and speak English

Exclusion Criteria:

* Neurodevelopmental disability or neurocognitive disorder
* CBT or CR in the past 6 months

Where it's running

• University of Toronto Scarborough
  Scarborough Village, Ontario, Canada Recruiting
• Ontario Shores Centre for Mental Health Sciences (Ontario Shores)
  Whitby, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Michael W Best, PhD, C.Psych — University of Toronto Scarborough
• Study coordinator: Hanna Hamzai, HBSc
• Email: hanna.hamzai@mail.utoronto.ca
• Phone: 6476896098

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.