Trying the Kiso Mind smartphone app for people with schizophrenia spectrum disorders
Official title: Acceptability, Feasibility and Preliminary Outcomes of the Kiso Mind App for Outpatients With Schizophrenia Spectrum Disorders: A Randomized Controlled Pilot Trial
Run by Charite University, Berlin, Germany · NCT07395206 · Data updated 2026-11-12
This study tests whether the Kiso Mind smartphone app is acceptable, practical, and helpful for adults with schizophrenia or schizoaffective disorder alongside their usual care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Charite University, Berlin, Germany Academic / other |
| Locations | 1 site (Berlin, State of Berlin) |
| Status | Recruiting |
| Started | January 30, 2026 |
| Main results expected | June 30, 2026 |
| Study ends | June 30, 2026 |
| Registry record updated | March 3, 2026 |
| Trial ID | NCT07395206 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–65 with an ICD-10 diagnosis of schizophrenia (F20) or schizoaffective disorder (F25), who speak German, can use a smartphone, and are not acutely suicidal or receiving intensive psychotherapy are the intended participants.
✕Probably not a fit
People without a smartphone, with acute heavy substance abuse, serious neurological damage, active suicidality, current electroconvulsive therapy, or who are in intensive psychotherapy are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a randomized, parallel-group pilot trial comparing access to the Kiso Mind smartphone app plus treatment-as-usual (TAU) versus TAU alone over 12 weeks. Participants diagnosed with ICD-10 schizophrenia (F20) or schizoaffective disorder (F25) complete baseline and 12-week self-report and rater-based assessments, and a subset in the app arm take part in a qualitative interview. Eligibility screening and clinician ratings are done centrally via video by research associates at Charité Berlin, and randomization is handled independently in Hamburg. The study aims to recruit about 60–80 participants across Germany to test acceptability, feasibility, and preliminary outcomes.
Why it matters
Potential benefit: If successful, the app could offer accessible, smartphone-based support to help people with schizophrenia manage symptoms and daily functioning alongside standard care.
How similar studies have gone: Prior pilot studies of smartphone apps for psychotic disorders have shown feasibility and some symptom or functioning improvements in small samples, but robust large-scale evidence remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ICD-10: F20 Schizophrenia, F25 Schizoaffective Disorder * Age: 18 - 65 years * Sufficient German Language Proficiency * Ability to Use a Smartphone Exclusion Criteria: * Intensive Psychotherapy Protocols (more than one psychotherapy session a month) * CGI-Score \< 3; \> 6 * No smartphone * Neurological Disorders or Brain Damage * Acute Suicidality * Acute Heavy Substance Abuse or Addiction * Current Electroconvulsive Therapy
Where it's running
-
Charité - Universitätsmedizin Berlin
Berlin, State of Berlin, Germany Recruiting
Study contacts
- Study coordinator: Pawel Weinstein, M.Sc.
- Email: pawel.weinstein@charite.de
- Phone: 0049 30 450 617 325
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Examining the effects of combined therapy for schizophrenia
This study is testing whether combining two therapies, one for managing thoughts and another for improving cognitive skills, can help people with schizophrenia do better in their daily lives compared to using just one of the therapies.
-
Theta-Burst Transcranial Magnetic Stimulation for Treatment-Resistant Auditory Hallucinations
This study tests whether theta-burst transcranial magnetic stimulation can lessen persistent auditory verbal hallucinations in adults with schizophrenia-spectrum or psychotic disorders who have not responded to antipsychotic meds.
-
State Representation in Early Psychosis 2
This observational study tests how people with early psychosis and healthy individuals use state information during tasks and how brain activity supports it.
-
Improving rehabilitation for veterans with serious mental illness
This study is testing a new computer program to help veterans with serious mental illnesses improve their thinking and daily life skills.
-
Using Lumateperone to improve motivation in patients with schizophrenia and psychosis
This study is testing if Lumateperone can help people with schizophrenia or schizoaffective disorders feel more motivated and less apathetic.
-
Using magnetic stimulation to improve cognition in psychotic disorders
This study is testing whether a type of brain stimulation called TMS can help improve thinking skills in people with psychotic disorders like schizophrenia and bipolar disorder.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.