Clinical trial Recruiting at 4 sites Interventional Ages 18 and up

Relaxation and breathing techniques to help with breathlessness and tiredness in cancer patients in palliative care

Official title: The Effect of Progressive Muscle Relaxation and Deep Breathing Exercises Applied to Palliative Care Cancer Patients on Dyspnea, Fatigue, and Self-Care Behaviors

Run by Ankara University · NCT07619209 · Data updated 2026-11-12

This study tests whether progressive muscle relaxation or deep breathing exercises can reduce dyspnea and fatigue and improve self-care in adults with cancer receiving palliative care.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment90 (estimated)
SponsorAnkara University
Academic / other
Locations4 sites (Ankara, YENIMAHALLE and 3 other locations)
StatusRecruiting
StartedJanuary 1, 2026
Main results expectedNovember 2026
Study endsDecember 2026
Registry record updatedJune 3, 2026
Trial IDNCT07619209 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older with confirmed cancer receiving palliative care, able to read/write, and meeting specific health criteria to participate.

Probably not a fit

Patients with certain respiratory diseases or cognitive impairments or those already practicing PMR/deep breathing may be less likely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two non-pharmacological approaches—progressive muscle relaxation and structured deep breathing exercises—delivered to adults with cancer in a palliative care setting. Participants are assigned to one of the two relaxation-based interventions to see if they can lessen breathlessness and fatigue and promote better self-care behaviors. The trial emphasizes routine, teachable techniques that patients can perform to improve comfort and daily functioning while managing advanced illness. Eligibility includes adults 18 or older with cancer, adequate communication abilities, and specific clinical criteria relevant to palliative care. The study is conducted at multiple palliative care units in Ankara, led by Ankara University.

Why it matters

Potential benefit: If successful, patients may experience reduced breathlessness and fatigue and improved ability to manage daily self-care.

How similar studies have gone: Nonpharmacologic relaxation techniques have shown potential benefits in symptom management for cancer patients in palliative care contexts, though this exact comparison is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being 18 years of age or older

Being literate (able to read and write)

Having no significant hearing or visual impairment that prevents communication or cooperation

Receiving treatment in the palliative care unit

Having a confirmed medical diagnosis of cancer

Having a Glasgow Coma Scale (GCS) score of 10 or higher

Being able to communicate via telephone and SMS for post-discharge follow-up

Having a Common Terminology Criteria for Adverse Events (CTCAE) Dyspnea Classification of Grade 3 or below

Having an ECOG Performance Status Scale score of 3 or below

Having a Hemoglobin (Hb) value of 8 gm/dL or higher

Volunteering to participate in the study and providing informed consent

Exclusion Criteria:

* Currently practicing or having recently practiced Progressive Muscle Relaxation (PMR) or deep breathing exercises actively

Having a primary respiratory system disease diagnosis (such as COPD, asthma, or pneumonia)

Having a medical diagnosis of dementia, agitation, or delirium

Receiving Continuous Positive Airway Pressure (CPAP) or Bilevel Positive Airway Pressure (BiPAP) support

Being on active antipsychotic or sedative medical treatment

Having a Common Terminology Criteria for Adverse Events (CTCAE) Dyspnea Classification of Grade 4 or higher

Where it's running

  • Ankara Gazi Mustafa Kemal Occupational and Environmental Diseases Hospital, Palliative Care Unit
    Ankara, Yenimahalle, Turkey (Türkiye)
    Recruiting
  • Ankara Ataturk Sanatorium Training and Research Hospital,Palliative Care Unit
    Ankara, Turkey (Türkiye)
    Recruiting
  • Ankara Sincan Training and Research Hospital, Palliative Care Unit
    Ankara, Turkey (Türkiye)
    Recruiting
  • Gulhane Training and Research Hospital, Palliative Care Unit
    Ankara, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.