Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Virtual Group Resilient Living for Advanced Cancer

Official title: Virtual Group Resilient Living Program For Patients Living With Advanced Cancer

Run by Mayo Clinic · NCT07659158 · Data updated 2026-11-12

A group-based online program tests whether seven weekly sessions can reduce anxiety and fatigue and improve quality of life for adults with advanced cancer.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment42 (estimated)
SponsorMayo Clinic
Academic / other
Locations1 site (Rochester, Minnesota)
StatusRecruiting
StartedJune 19, 2026
Main results expectedJune 30, 2027
Study endsJune 30, 2027
Registry record updatedJuly 2, 2026
Trial IDNCT07659158 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with advanced (stage III/IV) cancer, English-speaking, with baseline distress, internet access, and the ability to participate in seven online group sessions and complete surveys.

Probably not a fit

Patients without significant distress or those unable to engage in online sessions may see little or no personal benefit from the program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-arm study conducted virtually at Mayo Clinic to test the feasibility and potential benefits of a 7-week Virtual Group Resilient Living Program. Participants learn stress-management and resilience techniques such as mindfulness, positive reframing, gratitude, compassion, acceptance, meaning, and forgiveness in a group setting, with the aim of improving anxiety, stress, quality of life, coping, and fatigue. The study also collects survey data to assess feasibility and preliminary effectiveness, and is designed for minimal risk. Eligibility requires adults with stage III/IV cancer, baseline distress, English fluency, internet access, and ability to participate in online sessions.

Why it matters

Potential benefit: If successful, participants may experience reduced anxiety and fatigue and improved quality of life through enhanced coping and resilience.

How similar studies have gone: Prior psychosocial programs with online group formats have shown feasibility and potential benefits in cancer populations, but this specific seven-session virtual resilience program is being explored for feasibility and signals of effectiveness.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English fluency
* Diagnosis of advanced (stage III/IV) malignancy
* Baseline distress score ≥ 4/10. Patients can answer questions orally rather than complete worksheet, if applicable
* Life expectancy of ≥ 6 months
* Provide informed consent
* Ability to complete questionnaire(s) by themselves or with assistance
* Has a reliable internet connection
* Has the ability to utilize technology to watch online modules, \& participate in virtual sessions

Exclusion Criteria:

* As determined through self-report, those diagnosed with a history of a psychotic episode ≤ 5 years
* All psychological co-morbidities such as a history of untreated schizophrenia, \& bipolar disease
* A diagnosis of severe cognitive impairment

Where it's running

  • Mayo Clinic in Rochester
    Rochester, Minnesota, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.