Comparing xenograft mixed with vitamin D to hyaluronic acid for immediate dental implants

Immediate Implant Placement Using Xenograft As Space Filling Material Mixed with Vitamin D Versus Hyaluronic Acid in Posterior Mandible Region: a Randomized Controlled Clinical Trial.

Not applicable Interventional Cairo University · NCT06842368

This study tests whether using a mix of vitamin D with a type of bone graft works better than hyaluronic acid for placing immediate dental implants in the back of the jaw.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorCairo University Academic / other
Locations1 site (Cairo)
Trial IDNCT06842368 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of immediate dental implant placement using xenograft mixed with vitamin D compared to hyaluronic acid in the posterior mandible region. It focuses on the stability and density of implants placed in fresh extraction sockets, addressing the critical space defect known as the jumping gap. By utilizing biological mediators in the biomaterials, the study aims to enhance bone quality and quantity, which are essential for the success of dental implants.

Who should consider this trial

Good fit: Ideal candidates are systemically healthy individuals aged 18-60 who require single or multiple immediate implants in the posterior teeth region.

Not a fit: Patients with systemic diseases affecting surgical outcomes, heavy smokers, or those with psychological issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could improve the success rate and longevity of immediate dental implants for patients.

How similar studies have performed: While there is ongoing research in the field of dental implants, this specific combination of xenograft and vitamin D is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age: 18-60.

* Systemically healthy patients indicated for single or multiple immediate implants in posterior teeth region.
* Absence of any peri-apical pathosis.
* Patients with intact buccal plate of bone.
* Patients with adequate bone volume for the dental implant procedure.
* Patient with good oral hygrine

Exclusion Criteria:

* Heavy Smokers.
* Systemic disease that may affect the final outcome of the surgical procedure.
* No or poor patient's compliance.
* Patients with psychological problems.
* Pathology at the site of intervention.
* Patient with vit d deficiency

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Immediate Implant PlacementHyaluronic acidVitamin DXenograftImmediate Implant
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.