Clinical trial Recruiting at 1 site Interventional Ages 18 to 60

Comparing xenograft mixed with vitamin D to hyaluronic acid for immediate dental implants

Official title: Immediate Implant Placement Using Xenograft As Space Filling Material Mixed with Vitamin D Versus Hyaluronic Acid in Posterior Mandible Region: a Randomized Controlled Clinical Trial.

Run by Cairo University · NCT06842368 · Data updated 2026-11-12

This study tests whether using a mix of vitamin D with a type of bone graft works better than hyaluronic acid for placing immediate dental implants in the back of the jaw.

More Immediate Implant Placement trials

Quick facts

Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment24 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedFebruary 2, 2025
Main results expectedSeptember 30, 2025
Study endsOctober 30, 2025
Registry record updatedFebruary 24, 2025
Trial IDNCT06842368 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are systemically healthy individuals aged 18-60 who require single or multiple immediate implants in the posterior teeth region.

Probably not a fit

Patients with systemic diseases affecting surgical outcomes, heavy smokers, or those with psychological issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of immediate dental implant placement using xenograft mixed with vitamin D compared to hyaluronic acid in the posterior mandible region. It focuses on the stability and density of implants placed in fresh extraction sockets, addressing the critical space defect known as the jumping gap. By utilizing biological mediators in the biomaterials, the study aims to enhance bone quality and quantity, which are essential for the success of dental implants.

Why it matters

Potential benefit: If successful, this approach could improve the success rate and longevity of immediate dental implants for patients.

How similar studies have gone: While there is ongoing research in the field of dental implants, this specific combination of xenograft and vitamin D is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age: 18-60.

* Systemically healthy patients indicated for single or multiple immediate implants in posterior teeth region.
* Absence of any peri-apical pathosis.
* Patients with intact buccal plate of bone.
* Patients with adequate bone volume for the dental implant procedure.
* Patient with good oral hygrine

Exclusion Criteria:

* Heavy Smokers.
* Systemic disease that may affect the final outcome of the surgical procedure.
* No or poor patient's compliance.
* Patients with psychological problems.
* Pathology at the site of intervention.
* Patient with vit d deficiency

Where it's running

  • Faculty of dentistry ,Cairo university
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.