Comparing xenograft mixed with vitamin D to hyaluronic acid for immediate dental implants
Official title: Immediate Implant Placement Using Xenograft As Space Filling Material Mixed with Vitamin D Versus Hyaluronic Acid in Posterior Mandible Region: a Randomized Controlled Clinical Trial.
Run by Cairo University · NCT06842368 · Data updated 2026-11-12
This study tests whether using a mix of vitamin D with a type of bone graft works better than hyaluronic acid for placing immediate dental implants in the back of the jaw.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 24 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | February 2, 2025 |
| Main results expected | September 30, 2025 |
| Study ends | October 30, 2025 |
| Registry record updated | February 24, 2025 |
| Trial ID | NCT06842368 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are systemically healthy individuals aged 18-60 who require single or multiple immediate implants in the posterior teeth region.
✕Probably not a fit
Patients with systemic diseases affecting surgical outcomes, heavy smokers, or those with psychological issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of immediate dental implant placement using xenograft mixed with vitamin D compared to hyaluronic acid in the posterior mandible region. It focuses on the stability and density of implants placed in fresh extraction sockets, addressing the critical space defect known as the jumping gap. By utilizing biological mediators in the biomaterials, the study aims to enhance bone quality and quantity, which are essential for the success of dental implants.
Why it matters
Potential benefit: If successful, this approach could improve the success rate and longevity of immediate dental implants for patients.
How similar studies have gone: While there is ongoing research in the field of dental implants, this specific combination of xenograft and vitamin D is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Age: 18-60. * Systemically healthy patients indicated for single or multiple immediate implants in posterior teeth region. * Absence of any peri-apical pathosis. * Patients with intact buccal plate of bone. * Patients with adequate bone volume for the dental implant procedure. * Patient with good oral hygrine Exclusion Criteria: * Heavy Smokers. * Systemic disease that may affect the final outcome of the surgical procedure. * No or poor patient's compliance. * Patients with psychological problems. * Pathology at the site of intervention. * Patient with vit d deficiency
Where it's running
-
Faculty of dentistry ,Cairo university
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Ammar Eiz Eddin
- Email: ammar.adib@dentistry.cu.edu.eg
- Phone: 00201153383058
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Socket-shield versus conventional immediate implant placement in the front jaw
This trial tests whether using the socket-shield technique during immediate implant placement in the upper front teeth better preserves bone and gum health than the standard method.
-
Magnesium membrane versus dual‑zone grafting for immediate implant placement in the aesthetic zone
This will test whether a magnesium membrane combined with bovine bone gives better bone and gum volume, improved esthetics, and less pain than dual‑zone grafting for adults receiving immediate implants in the upper front teeth.
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Labial bone preservation after immediate implant placement using two xenografts in the esthetic zone
This trial will see if two different xenograft materials help preserve the labial bone plate when placing immediate implants in Type II extraction sockets in the upper front jaw.
-
Osseodensification forMol ar Septum Expansion in Immediate Molar Implants
This study tests whether osseodensification helps place immediate molar implants more stably compared with traditional drilling, in adults needing extraction and replacement teeth.
-
Comparing two types of platelet-rich fibrin for dental implants
This study is testing which of two types of platelet-rich fibrin helps dental implants work better for patients getting immediate implants after losing their back teeth.
-
Evaluating Doxycycline Nanoparticles with Gelatin Sponge for Immediate Dental Implants
This study tests if using doxycycline nanoparticles with a gelatin sponge can improve the success of immediate dental implants compared to standard treatment for patients getting implants in the front of their mouth.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.