Magnesium membrane versus dual‑zone grafting for immediate implant placement in the aesthetic zone
Evaluation of the Magnesium Shield Compared to Dual Zone Grafting Approach in Immediate Implant Site Management: a Randomized Controlled Clinical Trial
This will test whether a magnesium membrane combined with bovine bone gives better bone and gum volume, improved esthetics, and less pain than dual‑zone grafting for adults receiving immediate implants in the upper front teeth.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 22 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | British University In Egypt Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Cairo) |
| Trial ID | NCT07492576 on ClinicalTrials.gov |
What this trial studies
Adults with hopeless maxillary anterior teeth and a thin buccal plate (≤1 mm) will receive immediate implant placement and be treated with either a magnesium membrane plus inorganic bovine bone placed between the membrane and implant, or with the dual‑zone grafting technique where graft material is placed in both bone and tissue zones. Key outcomes include socket volume gain, pink esthetic score, and patient pain measured by a visual analogue scale, with assessments at planned follow‑up visits. Eligible participants are 18–60 years old, periodontally healthy, non‑smokers, medically controlled, and without recent chemotherapy/radiotherapy or acute infection. The interventional procedures and follow‑up are conducted at the British University in Egypt in Cairo.
Who should consider this trial
Good fit: Adults 18–60 with hopeless upper front teeth, a thin buccal plate (≤1 mm), healthy gums, controlled medical conditions, and who are non‑smokers without recent chemotherapy/radiation or acute infections.
Not a fit: Patients who smoke, have uncontrolled systemic disease, recent chemotherapy or radiotherapy, acute infection, or who do not have a thin buccal plate in the aesthetic zone are unlikely to qualify or benefit.
Why it matters
Potential benefit: If successful, the magnesium membrane approach could better preserve bone and gum contours around immediate implants, improving esthetic results and patient comfort.
How similar studies have performed: The dual‑zone grafting concept is an established method for preserving soft‑tissue contour, while magnesium membranes with bovine bone are a newer approach with limited but promising early reports.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-60 years of age * Patients have hopeless maxillary teeth, a thin buccal plate of bone ≤1 mm and intact overlying soft tissue intact overlying soft tissues in aesthetic zone (EDS-2, Kan classification) * Periodontally healthy (good oral hygiene) * Medically controlled patient Exclusion Criteria: * Smokers * patients with systemic diseases * history of chemotherapy or radiotherapy within the past 2 years. * Acute infection
Where this trial is running
Cairo
- The British university in Egypt — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Rim M Ghanem, Bachelor degree of dentistry
- Email: rim.mazen@bue.edu.eg
- Phone: 0106037279
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.