Evaluating Doxycycline Nanoparticles with Gelatin Sponge for Immediate Dental Implants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to assess the effectiveness of doxycycline nanoparticles combined with a gelatin sponge in enhancing the outcomes of immediate dental implant placements in the esthetic zone. The study will involve two groups of patients: one receiving implants with doxycycline-loaded nanoparticles and gelatin sponge, and the other receiving implants with standard doxycycline and gelatin sponge. Researchers will compare clinical and radiographic results between these two groups to determine if the nanoparticle formulation provides superior benefits.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The presence of non-restorable single-rooted maxillary centrals, canines or premolars.
* Sufficient bone volume.
* Good oral hygiene.
* The remaining space between the socket and the fixture equals or more than 2mm at the coronal third of the socket.
* Sufficient bone width (≥ 1 mm) in the buccal plate of the remaining bone to place an implant confirmed by cone beam computer tomography (CBCT).

Exclusion Criteria:

* Insufficient bone volume.
* Active infection.
* Patients on chemotherapy or radiotherapy.
* Patients who have systemic disorders {uncontrolled diabetes mellitus, autoimmune disease, …etc},
* Pregnant patients,
* Patients with bone diseases
* Presence of periapical pathology affecting the neighbouring teeth.
* Smokers.

Where it's running

• Faculty of dentistry kafrelsheikh university
  Kafrelsheikh, Kafrelsheikh, Egypt Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.