Comparing walking analysis after knee replacement using different alignment methods

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the outcomes of total knee arthroplasty (TKA) by comparing two alignment techniques: kinematic alignment and mechanical alignment. The study focuses on patients aged 55 to 80 with disabling knee osteoarthritis who are undergoing their first unilateral TKA. Participants will be assessed for their walking ability and satisfaction post-surgery, aiming to determine which alignment method leads to better functional results and patient satisfaction. The trial is conducted at Hôpital de la Croix Rousse in Lyon.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Both sex
* Adults between 55 and 80 years
* Diagnosis of internal or global disabling femorotibial gonarthrosis Indication of total first knee arthroplasty (unilateral), using a Sphere type prosthesis (Medacta)
* Constitutional deformity in varus between 3 ° and 10 °
* Fulfilling the pass conditions of a KneeKG walking test: Unipodal support possible for 1 minute, run for 5 min at a speed of at least 0.8 km / h
* Affiliated to a social security system
* Patients able to understand and fulfill the requirement of the study

Exclusion Criteria:

* TKA bilateral
* TKA to change an Uni-compartmental prosthesis
* History of femoral or tibial fracture
* History of femoral or tibial osteotomy
* Associated gesture at the same time (allograft, osteotomy)
* External femorotibial gonarthrosis
* Angle Hip Knee Ankle \> 178 °
* Constitutional distortion\> 10 °
* Refusal to participate in the study
* Persons deprived of their liberty by a judicial or administrative decision, persons under psychiatric care, persons admitted to a health or social institution for purposes other than research
* Adults subject to a legal protection measure
* breastfeeding or pregnant women
* Patient already participating to another clinical trial that might jeopardize the current trial

Where it's running

• Hôpital de la Croix Rousse
  Lyon, France Recruiting

Study contacts

• Principal investigator: Sebastien Lustig, Pr — Hospices Civils de Lyon
• Study coordinator: Sebastien Lustig, Pr
• Email: sebastien.lustig@chu-lyon.fr
• Phone: 4 26 10 92 98

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.