Adductor canal block versus adductor canal plus IPACK block for pain after total knee replacement
Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Block Combined With Local Anesthetic Infiltration Between the Popliteal Artery and the Capsule of the Knee (IPACK) in Patients Undergoing Knee Surgery
This study will test whether adding an IPACK block to an adductor canal block reduces pain and the need for pain medicine after total knee replacement.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | TC Erciyes University Academic / other |
| Locations | 2 sites (Kayseri, Talas and 1 other locations) |
| Trial ID | NCT07526831 on ClinicalTrials.gov |
What this trial studies
In patients undergoing total knee arthroplasty, clinicians will compare postoperative pain and analgesic use between those receiving an ultrasound-guided adductor canal block alone and those receiving an adductor canal block combined with an IPACK block. The observational protocol groups patients into Adductor Canal Block (Group I) and Adductor Canal + IPACK Block (Group II) based on the analgesic technique used. Outcomes include postoperative pain scores and analgesic requirements, with blocks performed under ultrasound guidance. Eligible adults are ASA I–III and exclusions include allergy to the study medication or refusal to participate.
Who should consider this trial
Good fit: Adults scheduled for total knee arthroplasty with ASA physical status I–III who can receive peripheral nerve blocks and consent to participate.
Not a fit: Patients with a known allergy to local anesthetics, those who refuse nerve blocks, or people with contraindications to regional anesthesia may not receive benefit.
Why it matters
Potential benefit: If successful, adding an IPACK block could improve pain control and reduce opioid use after total knee arthroplasty.
How similar studies have performed: Previous reports and trials have shown that combining an IPACK block with an adductor canal block can provide better posterior knee analgesia and lower opioid consumption in many studies, though results are not uniformly conclusive.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA (American Society of Anesthesiologists) I- ASA II-ASA III Patients Exclusion Criteria: * history of allergy to the study medication * refusal to participate
Where this trial is running
Kayseri, Talas and 1 other locations
- Sibel Pehlivan — Kayseri, Talas, Turkey (Türkiye) (Recruiting)
- Sibel Seckin Pehlivan — Kayseri, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Sibel Pehlivan, DR
- Email: Sibelpehlivan@erciyes.edu.tr
- Phone: 0905052532919
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.