Comparing two types of nerve blocks for pain management after knee surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of a single-shot adductor canal block (ACB) versus a continuous femoral nerve block (FNB) for managing postoperative pain in patients undergoing total knee replacement. The goal is to determine which method provides better pain relief while minimizing motor impairment and enhancing recovery. ACB is hypothesized to offer similar analgesia without affecting the quadriceps muscle function, potentially leading to improved rehabilitation outcomes. Participants will be monitored for pain levels, functional recovery, and any complications related to the nerve blocks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18
* Planned primary total knee replacement
* Planned neuraxial anesthesia
* Written informed consent

Exclusion Criteria:

* Urgent surgery
* Planned revision total knee replacement
* Known allergic reaction to anesthetics
* Confirmed localized infection at the puncture sites
* Confirmed localized tumor at the puncture sites
* Peripheral neuropathy of the lower extremities
* Parkinson's disease
* Previously enrolled in this trial

Where it's running

• Clinical Hospital on Yauza
  Moscow, Russia Recruiting

Study contacts

• Principal investigator: Valery Likhvantsev — Negovsky Reanimatology Research Institute
• Study coordinator: Valery Likhvantsev
• Email: lik0704@gmail.com
• Phone: +79036235982

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Tail Fat Application for Knee Osteoarthritis Pain and Stiffness

  This study tests whether applying sheep tail fat to the knee helps reduce pain and stiffness and improves daily activity in adults with gonarthrosis.

  Recruiting at 2 sites Inonu University · Bitlis and 1 other locations · NCT07867405

• Knee Osteoarthritis: See If Your Treatment Beliefs Help Your Physical Therapy

  This study will look to see if what patients expect from physical therapy influences the benefits they get for knee osteoarthritis.

  Recruiting Gazi University · Ankara, Yenimahalle · NCT07618403

• Arthrosamid versus steroid injections for managing knee osteoarthritis.

  This trial will test whether a single Arthrosamid hydrogel injection works better than a standard steroid plus local anesthetic injection for adults with symptomatic knee osteoarthritis.

  Recruiting Phase 4 Cappagh National Orthopaedic Hospital · Dublin, Dublin · NCT07489521

• Oral vs IV Dexamethasone in Knee Replacement Recovery

  This real-world study compares how giving dexamethasone by mouth or by IV around knee replacement affects early pain, movement, and recovery.

  Recruiting Haseki Training and Research Hospital · Istanbul, Istanbul · NCT07442812

• Combined intra‑articular and peri‑articular PRP injections for chronic knee osteoarthritis

  This will test whether adding ultrasound-guided peri‑articular PRP injections to intra‑articular PRP helps adults 40–65 with moderate medial knee osteoarthritis have less pain and better function.

  Recruiting Ankara City Hospital Bilkent · Ankara, Çankaya · NCT07339137

• Bimodal vs Unimodal High-Intensity Pulsed Electromagnetic Field Therapy for Older Adults with Knee Osteoarthritis

  This trial will test whether applying high-intensity pulsed electromagnetic fields to both the knee and quadriceps reduces pain and improves function more than applying it only to the knee in adults 60 and older with knee osteoarthritis.

  Recruiting Hospital Civil de Guadalajara · Guadalajara, Jalisco · NCT07198750

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.