Comparing two types of nerve blocks for pain management after knee surgery
The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement (AdORe - ACB)
This study is testing whether a single injection of a nerve block can help control pain after knee surgery better than a continuous nerve block, while also allowing for easier movement and recovery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 220 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Negovsky Reanimatology Research Institute Government |
| Locations | 1 site (Moscow) |
| Trial ID | NCT05487053 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness of a single-shot adductor canal block (ACB) versus a continuous femoral nerve block (FNB) for managing postoperative pain in patients undergoing total knee replacement. The goal is to determine which method provides better pain relief while minimizing motor impairment and enhancing recovery. ACB is hypothesized to offer similar analgesia without affecting the quadriceps muscle function, potentially leading to improved rehabilitation outcomes. Participants will be monitored for pain levels, functional recovery, and any complications related to the nerve blocks.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are scheduled for primary total knee replacement and can provide informed consent.
Not a fit: Patients requiring urgent surgery, those with specific contraindications, or those who have previously participated in this trial may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies that enhance recovery and reduce complications after total knee replacement.
How similar studies have performed: Previous studies have shown promising results with adductor canal blocks, suggesting they may be a viable alternative to femoral nerve blocks, but this specific comparison is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 * Planned primary total knee replacement * Planned neuraxial anesthesia * Written informed consent Exclusion Criteria: * Urgent surgery * Planned revision total knee replacement * Known allergic reaction to anesthetics * Confirmed localized infection at the puncture sites * Confirmed localized tumor at the puncture sites * Peripheral neuropathy of the lower extremities * Parkinson's disease * Previously enrolled in this trial
Where this trial is running
Moscow
- Clinical Hospital on Yauza — Moscow, Russia (Recruiting)
Study contacts
- Principal investigator: Valery Likhvantsev — Negovsky Reanimatology Research Institute
- Study coordinator: Valery Likhvantsev
- Email: lik0704@gmail.com
- Phone: +79036235982
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.