Comparing techniques for placing central venous catheters
Official title: A Randomized Study Comparing Two Techniques for Central Venous Catheter Insertion
Run by Montefiore Medical Center · NCT05534971 · Data updated 2026-11-12
This study is testing whether using a peripheral intravenous catheter is a better and safer way to place central venous catheters in adults in the emergency department compared to the traditional method.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 160 (estimated) |
| Sponsor | Montefiore Medical Center Academic / other |
| Locations | 1 site (The Bronx, New York) |
| Status | Recruiting |
| Started | November 16, 2022 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | January 6, 2026 |
| Trial ID | NCT05534971 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult patients in the emergency department needing ultrasound-guided central line placement.
✕Probably not a fit
Patients with coagulopathy, previous central venous access at the same site, or other conditions that interfere with consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares two techniques for central venous catheterization, focusing on the use of a peripheral intravenous catheter versus the traditional wire through hollow bore needle method. The hypothesis is that the peripheral technique will result in higher success rates on the first attempt, fewer complications, and a quicker procedure time. The study will involve adult patients in the emergency department who require this lifesaving procedure, utilizing ultrasound guidance to enhance accuracy. The goal is to determine which method is more effective and safer for patients requiring central venous access.
Why it matters
Potential benefit: If successful, this study could improve the efficiency and safety of central venous catheter placements in emergency settings.
How similar studies have gone: Previous research has shown promise for similar techniques, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Adult patients in the emergency department who require ultrasound guided central line placement are eligible for participation and will be referred for participation in the study by the clinical team. Exclusion Criteria: * Inherited, acquired, or medication related coagulopathy or thrombocytopenia (platelets \< 100,000). Patients will not be excluded for use of aspirin or other anti-platelet medication. * Previous central venous access at the same anatomical site. * Any indwelling catheter or wire that could potentially interfere with central line placement * Anterior border of the target vein deeper than 3.5cm Or for any clinical feature that would interfere with obtaining informed consent including dementia, delirium, or encephalopathy, as determined by the clinical attending physician.
Where it's running
-
Montefiore
The Bronx, New York, United States Recruiting
Study contacts
- Principal investigator: Benjamin J Friedman, MD — Montefiore Medical Center
- Study coordinator: Joe Offenbacher, MD
- Email: joseph.offenbacher@nyulangone.org
- Phone: 646-929-7815
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.