Comparing techniques for placing central venous catheters

A Randomized Study Comparing Two Techniques for Central Venous Catheter Insertion

This study is testing whether using a peripheral intravenous catheter is a better and safer way to place central venous catheters in adults in the emergency department compared to the traditional method.

Quick facts

• Phase: Phase 4
• Study type: Interventional
• Enrollment: 160 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: Montefiore Medical Center (Academic / other)
• Locations: 1 site (The Bronx, New York)
• Trial ID: NCT05534971 on ClinicalTrials.gov

What this trial studies

This study compares two techniques for central venous catheterization, focusing on the use of a peripheral intravenous catheter versus the traditional wire through hollow bore needle method. The hypothesis is that the peripheral technique will result in higher success rates on the first attempt, fewer complications, and a quicker procedure time. The study will involve adult patients in the emergency department who require this lifesaving procedure, utilizing ultrasound guidance to enhance accuracy. The goal is to determine which method is more effective and safer for patients requiring central venous access.

Who should consider this trial

Good fit: Ideal candidates are adult patients in the emergency department needing ultrasound-guided central line placement.

Not a fit: Patients with coagulopathy, previous central venous access at the same site, or other conditions that interfere with consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the efficiency and safety of central venous catheter placements in emergency settings.

How similar studies have performed: Previous research has shown promise for similar techniques, suggesting potential for success in this approach.

Eligibility criteria

Inclusion Criteria:

Adult patients in the emergency department who require ultrasound guided central line placement are eligible for participation and will be referred for participation in the study by the clinical team.

Exclusion Criteria:

* Inherited, acquired, or medication related coagulopathy or thrombocytopenia (platelets \< 100,000). Patients will not be excluded for use of aspirin or other anti-platelet medication.
* Previous central venous access at the same anatomical site.
* Any indwelling catheter or wire that could potentially interfere with central line placement
* Anterior border of the target vein deeper than 3.5cm

Or for any clinical feature that would interfere with obtaining informed consent including dementia, delirium, or encephalopathy, as determined by the clinical attending physician.

Where this trial is running

The Bronx, New York

• Montefiore — The Bronx, New York, United States (Recruiting)

Study contacts

• Principal investigator: Benjamin J Friedman, MD — Montefiore Medical Center
• Study coordinator: Joe Offenbacher, MD

Conditions Shock