Comparing oxygen targets with different oximeters for better oxygen flow management
Comparison of Two Oxygenation Targets With Two Different Oximeters - Impact on Oxygen Flow Rates and Oxygenation
This study tests whether using different types of oximeters can help manage oxygen flow better for patients recovering from heart surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Laval University Academic / other |
| Locations | 1 site (Québec, Quebec) |
| Trial ID | NCT05590130 on ClinicalTrials.gov |
What this trial studies
This study evaluates the impact of two different oximeters, Nonin and Philips, on oxygen flow rates and oxygenation targets in patients recovering from cardiac surgery. Participants will be assigned to different oximeters and SpO2 targets (90% and 94%) in a randomized manner, with arterial gas samples collected to assess oxygenation levels. The goal is to determine how the choice of oximeter and target saturation affects the required oxygen flow rates. This could lead to more effective oxygen management in postoperative care.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are admitted to a postoperative cardiac surgery intensive care unit and require conventional oxygen therapy.
Not a fit: Patients who are unable to provide a SpO2 signal with the oximeter or have conditions like methemoglobinemia or are in isolation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve oxygen management strategies, potentially reducing the risk of oxygen toxicity and respiratory failure in postoperative patients.
How similar studies have performed: While there have been studies on oximeter accuracy, this specific comparison of oxygen targets and their impact on flow rates is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥ 18 years of age * Patients admitted to postoperative cardiac surgery intensive care unit * Presence of an arterial catheter Specific for the extubate patient * Ongoing on conventional oxygen therapy at moderate flow (up to a maximum of 5L/min) with SpO2 between 88 and 100% with the usual oximeter and nasal cannula. * SpO2 \< 92% ambient air Specific for the intubate patient FiO2 \<= 0.60 with SpO2 between 88 and 100% with usual oximeter SpO2 \< 92% with FiO2 0.21 Exclusion Criteria: * No SpO2 signal with oximeter in use * False nails or nail polish * Methemoglobinemia \>0.015 on last available arterial gas * Patient in isolation (multi-resistant bacteria, C-Difficile, SARS-CoV-2 ...) Specific for the extubate patient * Expected to use another respiratory support within one hour of inclusion (NIV or nasal high flow oxygen) Planned extubation within one hour of inclusion
Where this trial is running
Québec, Quebec
- Institut Universitaire de Cardiologie et de Pneumologie de Québec — Québec, Quebec, Canada (Recruiting)
Study contacts
- Study coordinator: Francois Lellouche
- Email: francois.lellouche@criucpq.ulaval.ca
- Phone: 418656-8711
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.