Clinical trial Recruiting at 1 site Interventional Ages 18 to 50

Comparing microneedling treatments for acne scars

Official title: Comparison of Efficacy of Microneedling With Autologous Platelet-Rich Plasma vs Microneedling With Topical Insulin in the Treatment of Atrophic Acne Scars

Run by Khyber Teaching Hospital · NCT06978361 · Data updated 2026-11-12

This study is testing whether microneedling with Platelet Rich Plasma or with topical insulin works better to improve acne scars in people who haven't had treatment in the last six months.

Quick facts

Study typeInterventional
Ages18 Years to 50 Years
SexAll
Enrollment116 (estimated)
SponsorKhyber Teaching Hospital
Academic / other
Locations1 site (Peshawar, KPK ,Pakistan)
StatusRecruiting
StartedMarch 1, 2025
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedMay 18, 2025
Trial IDNCT06978361 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with post-acne atrophic scars who have not received any treatment for their scars in the past six months.

Probably not a fit

Patients with active acne, other skin conditions, or those who have received prior treatments for scars may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of two microneedling techniques for treating post-acne atrophic scars: one using autologous Platelet Rich Plasma (PRP) and the other using topical insulin. Patients with confirmed acne scars who have not undergone treatment in the last six months will be enrolled. The study aims to determine which method yields better results in scar improvement. By comparing these two interventions, the research seeks to provide insights into optimal treatment options for acne scars.

Why it matters

Potential benefit: If successful, this study could offer a more effective treatment option for patients suffering from post-acne atrophic scars.

How similar studies have gone: While there have been studies on microneedling and PRP, the specific comparison of microneedling with topical insulin is less common, making this approach somewhat novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patients confirmed with post-acne atrophic scars . No prior treatment for scars in last 6 months.

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Exclusion Criteria:

* Patient with active acne or other skin conditions (e.g eczema , psoriasis). Patients on oral or topical retinoids. Pregnant or lactating Mothers. Patients with recurrent herpes simplex infection. Previous Hx of keloids / hypertrophic scarring. Deranged blood glucose levels. Bleeding disorders

Where it's running

  • Khyber Teaching Hospital
    Peshawar, KPK ,Pakistan, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.