Comparing microneedling treatments for acne scars
Comparison of Efficacy of Microneedling With Autologous Platelet-Rich Plasma vs Microneedling With Topical Insulin in the Treatment of Atrophic Acne Scars
This study is testing whether microneedling with Platelet Rich Plasma or with topical insulin works better to improve acne scars in people who haven't had treatment in the last six months.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 116 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Khyber Teaching Hospital Academic / other |
| Locations | 1 site (Peshawar, KPK ,Pakistan) |
| Trial ID | NCT06978361 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of two microneedling techniques for treating post-acne atrophic scars: one using autologous Platelet Rich Plasma (PRP) and the other using topical insulin. Patients with confirmed acne scars who have not undergone treatment in the last six months will be enrolled. The study aims to determine which method yields better results in scar improvement. By comparing these two interventions, the research seeks to provide insights into optimal treatment options for acne scars.
Who should consider this trial
Good fit: Ideal candidates are patients with post-acne atrophic scars who have not received any treatment for their scars in the past six months.
Not a fit: Patients with active acne, other skin conditions, or those who have received prior treatments for scars may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could offer a more effective treatment option for patients suffering from post-acne atrophic scars.
How similar studies have performed: While there have been studies on microneedling and PRP, the specific comparison of microneedling with topical insulin is less common, making this approach somewhat novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients confirmed with post-acne atrophic scars . No prior treatment for scars in last 6 months. \- Exclusion Criteria: * Patient with active acne or other skin conditions (e.g eczema , psoriasis). Patients on oral or topical retinoids. Pregnant or lactating Mothers. Patients with recurrent herpes simplex infection. Previous Hx of keloids / hypertrophic scarring. Deranged blood glucose levels. Bleeding disorders
Where this trial is running
Peshawar, KPK ,Pakistan
- Khyber Teaching Hospital — Peshawar, KPK ,Pakistan, Pakistan (Recruiting)
Study contacts
- Study coordinator: Soaiba Naeem, MBBS
- Email: soaiba91@gmail.com
- Phone: +923139493991
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.