Antireflux stitch during one-anastomosis gastric bypass

Antireflux Suture In Laparoscopic One Anastomsis Gastric Bypass Surgery, A Randomised Control Trial

Not applicable Interventional Khyber Teaching Hospital · NCT07148492

This study will test whether adding an antireflux stitch during one-anastomosis gastric bypass reduces postoperative reflux and vomiting for patients having that surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment316 (estimated)
SexAll
SponsorKhyber Teaching Hospital Academic / other
Locations1 site (Peshawar, Khyberpukhtunkhwa)
Trial IDNCT07148492 on ClinicalTrials.gov

What this trial studies

Patients undergoing one-anastomosis gastric bypass at Khyber Teaching Hospital will be compared between those who receive an antireflux suture at the anastomosis and those who do not. Postoperative symptoms of gastroesophageal reflux and vomiting will be recorded and compared between groups over the follow-up period. The trial aims to fill a gap in evidence about whether the suture reduces symptomatic reflux after this specific bariatric procedure. Participants will be recruited and followed at the single study site in Peshawar with standardized symptom monitoring.

Who should consider this trial

Good fit: Adults who are scheduled to undergo one-anastomosis gastric bypass at Khyber Teaching Hospital and who provide informed consent are eligible to participate.

Not a fit: Patients who are not undergoing one-anastomosis gastric bypass or who decline participation are not expected to benefit from this specific intervention within the study.

Why it matters

Potential benefit: If successful, adding the antireflux stitch could reduce postoperative reflux and vomiting and improve patients' recovery and quality of life after one-anastomosis gastric bypass.

How similar studies have performed: There is limited and inconclusive evidence so far about the benefit of an antireflux suture in this operation, so the approach remains incompletely tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing one anastomosis gastric bypass surgery

Exclusion Criteria:

* Non consenting individuals

Where this trial is running

Peshawar, Khyberpukhtunkhwa

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Reflux Disease, Gastro-EsophagealVomiting, Postoperative
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.