Antireflux stitch during one-anastomosis gastric bypass
Official title: Antireflux Suture In Laparoscopic One Anastomsis Gastric Bypass Surgery, A Randomised Control Trial
Run by Khyber Teaching Hospital · NCT07148492 · Data updated 2026-11-12
This study will test whether adding an antireflux stitch during one-anastomosis gastric bypass reduces postoperative reflux and vomiting for patients having that surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 316 (estimated) |
| Sponsor | Khyber Teaching Hospital Academic / other |
| Locations | 1 site (Peshawar, Khyberpukhtunkhwa) |
| Status | Recruiting |
| Started | January 1, 2024 |
| Main results expected | September 30, 2025 |
| Study ends | September 30, 2025 |
| Registry record updated | August 29, 2025 |
| Trial ID | NCT07148492 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults who are scheduled to undergo one-anastomosis gastric bypass at Khyber Teaching Hospital and who provide informed consent are eligible to participate.
✕Probably not a fit
Patients who are not undergoing one-anastomosis gastric bypass or who decline participation are not expected to benefit from this specific intervention within the study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Patients undergoing one-anastomosis gastric bypass at Khyber Teaching Hospital will be compared between those who receive an antireflux suture at the anastomosis and those who do not. Postoperative symptoms of gastroesophageal reflux and vomiting will be recorded and compared between groups over the follow-up period. The trial aims to fill a gap in evidence about whether the suture reduces symptomatic reflux after this specific bariatric procedure. Participants will be recruited and followed at the single study site in Peshawar with standardized symptom monitoring.
Why it matters
Potential benefit: If successful, adding the antireflux stitch could reduce postoperative reflux and vomiting and improve patients' recovery and quality of life after one-anastomosis gastric bypass.
How similar studies have gone: There is limited and inconclusive evidence so far about the benefit of an antireflux suture in this operation, so the approach remains incompletely tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing one anastomosis gastric bypass surgery Exclusion Criteria: * Non consenting individuals
Where it's running
-
Khyber teaching hospital
Peshawar, Khyberpukhtunkhwa, Pakistan Recruiting
Study contacts
- Study coordinator: Saeed Sarwar, MBBS
- Email: saeedkmc2020@gmail.com
- Phone: +923420973863
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.